PDB entry 2x0r

View 2x0r on RCSB PDB site
Description: R207S, R292S Mutant of Malate Dehydrogenase from the Halophilic Archeon Haloarcula marismortui (HoloForm)
Class: oxidoreductase
Keywords: protein-solvent interaction, haophilic, ion-binding, oxidoreductase, tricarboxylic acid cycle
Deposited on 2009-12-17, released 2009-12-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-06-13, with a file datestamp of 2018-06-08.
Experiment type: XRAY
Resolution: 2.92 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: malate dehydrogenase
    Species: Haloarcula marismortui [TaxId:2238]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07841 (Start-303)
      • engineered mutation (187)
      • engineered mutation (266)
    Domains in SCOPe 2.08: d2x0ra1, d2x0ra2
  • Chain 'B':
    Compound: malate dehydrogenase
    Species: Haloarcula marismortui [TaxId:2238]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07841 (Start-303)
      • engineered mutation (187)
      • engineered mutation (266)
    Domains in SCOPe 2.08: d2x0rb1, d2x0rb2
  • Heterogens: NAD, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2x0rA (A:)
    mtkvsvvgaagtvgaaagynialrdiadevvfvdipdkeddtvgqaadtnhgiaydsntr
    vrqggyedtagsdvvvitagiprqpgqtridlagdnapimediqssldehnddyisltts
    npvdllnrhlyeagdrsreqvigfggrldsarfryvlseefdapvqnvegtilgehgdaq
    vpvfskvsvdgtdpefsgdekeqllgdlqesamdvierkgatewgpargvahmveailhd
    tgevlpasvklegefghedtafgvpvslgsngveeivewdlddyeqdlmadaaeklsdqy
    dkis
    

    Sequence, based on observed residues (ATOM records): (download)
    >2x0rA (A:)
    tkvsvvgaagtvgaaagynialrdiadevvfvdipdkeddtvgqaadtnhgiaydsntrv
    rqggyedtagsdvvvitagiprqpgqtridlagdnapimediqssldehnddyislttsn
    pvdllnrhlyeagdrsreqvigfggrldsarfryvlseefdapvqnvegtilgehgdaqv
    pvfskvsvdgtdpefsgdekeqllgdlqesamdvierkgatewgpargvahmveailhdt
    gevlpasvklegefghedtafgvpvslgsngveeivewdlddyeqdlmadaaeklsdqyd
    kis
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2x0rB (B:)
    mtkvsvvgaagtvgaaagynialrdiadevvfvdipdkeddtvgqaadtnhgiaydsntr
    vrqggyedtagsdvvvitagiprqpgqtridlagdnapimediqssldehnddyisltts
    npvdllnrhlyeagdrsreqvigfggrldsarfryvlseefdapvqnvegtilgehgdaq
    vpvfskvsvdgtdpefsgdekeqllgdlqesamdvierkgatewgpargvahmveailhd
    tgevlpasvklegefghedtafgvpvslgsngveeivewdlddyeqdlmadaaeklsdqy
    dkis
    

    Sequence, based on observed residues (ATOM records): (download)
    >2x0rB (B:)
    tkvsvvgaagtvgaaagynialrdiadevvfvdipdkeddtvgqaadtnhgiaydsntrv
    rqggyedtagsdvvvitagiprqpgqtridlagdnapimediqssldehnddyislttsn
    pvdllnrhlyeagdrsreqvigfggrldsarfryvlseefdapvqnvegtilgehgdaqv
    pvfskvsvdgtdpefsgdekeqllgdlqesamdvierkgatewgpargvahmveailhdt
    gevlpasvklegefghedtafgvpvslgsngveeivewdlddyeqdlmadaaeklsdqyd
    kis