PDB entry 2wxu

View 2wxu on RCSB PDB site
Description: Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I
Class: hydrolase
Keywords: cytolysis, hydrolase, hemolysis, membrane binding, virulence, gangrene determinant, c2 domain
Deposited on 2009-11-10, released 2009-11-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-10, with a file datestamp of 2019-04-05.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phospholipase c
    Species: CLOSTRIDIUM PERFRINGENS [TaxId:1502]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0TV31 (0-369)
      • engineered mutation (73)
      • conflict (334)
    Domains in SCOPe 2.08: d2wxua1, d2wxua2
  • Heterogens: CD, ZN, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wxuA (A:)
wdgkidgtgthamivtqgvsilendlsknepesvrknleilkenmhelqlgstypdydkn
aydlyqdhfwdpdidnnfskdnswylaysipdtgesqirkfsalaryewqrgnykqatfy
lgeamhyfgdidtpyhpanvtavdsaghvkfetfaeerkeqykintagcktneafytdil
knkdfnawskeyargfaktgksiyyshasmshswddwdyaakvtlansqkgtagyiyrfl
hdvsegndpsvgknvkelvayistsgekdagtddymyfgiktkdgktqewemdnpgndfm
tgskdtytfklkdenlkiddiqnmwirkrkytafpdaykpenikiiangkvvvdkdinew
isgnstynik

    Sequence, based on observed residues (ATOM records): (download) 
    >2wxuA (A:)
wdgkidgtgthamivtqgvsilendlsknepesvrknleilkenmhelqlgstypdydkn
aydlyqdhfwdpdiwylaysipdtgesqirkfsalaryewqrgnykqatfylgeamhyfg
didtpyhpanvtavdsaghvkfetfaeerkeqykintagcktneafytdilknkdfnaws
keyargfaktgksiyyshasmshswddwdyaakvtlansqkgtagyiyrflhdvsegndp
svgknvkelvayistsgekdagtddymyfgiktkdgktqewemdnpgndfmtgskdtytf
klkdenlkiddiqnmwirkrkytafpdaykpenikiiangkvvvdkdinewisgnstyni
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