PDB entry 2wwj

View 2wwj on RCSB PDB site
Description: structure of jmjd2a complexed with inhibitor 10a
Class: oxidoreductase
Keywords: chromatin regulator, double-stranded beta helix, oxidoreductase, transcription, oxygenase, host-virus interaction, transcription regulation
Deposited on 2009-10-23, released 2010-03-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-03-09, with a file datestamp of 2010-03-05.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.18104
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysine-specific demethylase 4a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75164 (Start-346)
    • PDB 2WWJ
    Domains in SCOPe 2.06: d2wwja_
  • Chain 'B':
    Compound: lysine-specific demethylase 4a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75164 (0-346)
    • PDB 2WWJ
    Domains in SCOPe 2.06: d2wwjb_
  • Heterogens: NI, ZN, Y28, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wwjA (A:)
tlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlv
ipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknlt
fnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfa
whtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlis
plmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlc
scrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaeft

    Sequence, based on observed residues (ATOM records): (download) 
    >2wwjA (A:)
lnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlvi
papiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknltf
nppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfaw
htedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlisp
lmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlcs
crkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaef

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wwjB (B:)
tlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlv
ipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknlt
fnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfa
whtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlis
plmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlc
scrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaeft

    Sequence, based on observed residues (ATOM records): (download) 
    >2wwjB (B:)
tlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlv
ipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknlt
fnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfa
whtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlis
plmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlc
scrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaef