PDB entry 2wwf

View 2wwf on RCSB PDB site
Description: Plasmodium falciparum thymidylate kinase in complex with TMP and ADP
Class: transferase
Keywords: transferase, kinase, malaria
Deposited on 2009-10-23, released 2010-04-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-03-25, with a file datestamp of 2015-03-20.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidilate kinase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I4S1 (2-211)
      • expression tag (1)
    Domains in SCOPe 2.08: d2wwfa1, d2wwfa2
  • Chain 'B':
    Compound: thymidilate kinase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wwfb_
  • Chain 'C':
    Compound: thymidilate kinase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I4S1 (2-211)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d2wwfc1, d2wwfc2
  • Heterogens: TMP, ADP, NA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wwfA (A:)
shmtddkkkgkfivfegldrsgkstqskllveylknnnvevkhlyfpnretgigqiisky
lkmensmsnetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktw
cmnpdqglikpdvvfylnvppnyaqnrsdygeeiyekvetqkkiyetykhfahedywini
datrkiedihndivkevtkikvepeefnflws

    Sequence, based on observed residues (ATOM records): (download) 
    >2wwfA (A:)
hmtddkkkgkfivfegldrsgkstqskllveylknnnvevkhlyfpnretgigqiiskyl
kmensmsnetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktwc
mnpdqglikpdvvfylnvppnyaqnrsdygeeiyekvetqkkiyetykhfahedywinid
atrkiedihndivkevtkikvepeefnflws

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wwfB (B:)
shmtddkkkgkfivfegldrsgkstqskllveylknnnvevkhlyfpnretgigqiisky
lkmensmsnetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktw
cmnpdqglikpdvvfylnvppnyaqnrsdygeeiyekvetqkkiyetykhfahedywini
datrkiedihndivkevtkikvepeefnflws

    Sequence, based on observed residues (ATOM records): (download) 
    >2wwfB (B:)
ddkkkgkfivfegldrsgkstqskllveylknnnvevkhlyfpnretgigqiiskylkme
nsmsnetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktwcmnp
dqglikpdvvfylnvppnyaqnrsdygeeiyekvetqkkiyetykhfahedywinidatr
kiedihndivkevtkikvepeefnflws

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wwfC (C:)
shmtddkkkgkfivfegldrsgkstqskllveylknnnvevkhlyfpnretgigqiisky
lkmensmsnetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktw
cmnpdqglikpdvvfylnvppnyaqnrsdygeeiyekvetqkkiyetykhfahedywini
datrkiedihndivkevtkikvepeefnflws