PDB entry 2wuf

View 2wuf on RCSB PDB site
Description: Crystal structure of S114A mutant of HsaD from Mycobacterium tuberculosis in complex with 4,9DSHA
Class: hydrolase
Keywords: hydrolase
Deposited on 2009-10-02, released 2009-10-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-12-19, with a file datestamp of 2018-12-14.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase bphd
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96851
      • engineered mutation (113)
    Domains in SCOPe 2.08: d2wufa_
  • Chain 'B':
    Compound: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase bphd
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96851
      • engineered mutation (113)
    Domains in SCOPe 2.08: d2wufb_
  • Heterogens: GOL, SCN, KEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wufA (A:)
mtateeltfestsrfaevdvdgplklhyheagvgndqtvvllhgggpgaaswtnfsrnia
vlarhfhvlavdqpgyghsdkraehgqfnryaamalkglfdqlglgrvplvgnalgggta
vrfaldyparagrlvlmgpgglsinlfapdptegvkrlskfsvaptrenleaflrvmvyd
knlitpelvdqrfalastpesltatramgksfagadfeagmmwrevyrlrqpvlliwgre
drvnpldgalvalktipraqlhvfgqcghwvqvekfdefnkltieflgggr

    Sequence, based on observed residues (ATOM records): (download) 
    >2wufA (A:)
ltfestsrfaevdvdgplklhyheagvgndqtvvllhgggpgaaswtnfsrniavlarhf
hvlavdqpgyghsdkraehgqfnryaamalkglfdqlglgrvplvgnalgggtavrfald
yparagrlvlmgpgglsinlfapdptegvkrlskfsvaptrenleaflrvmvydknlitp
elvdqrfalastpesltatramgksfagadfeagmmwrevyrlrqpvlliwgredrvnpl
dgalvalktipraqlhvfgqcghwvqvekfdefnkltieflg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wufB (B:)
mtateeltfestsrfaevdvdgplklhyheagvgndqtvvllhgggpgaaswtnfsrnia
vlarhfhvlavdqpgyghsdkraehgqfnryaamalkglfdqlglgrvplvgnalgggta
vrfaldyparagrlvlmgpgglsinlfapdptegvkrlskfsvaptrenleaflrvmvyd
knlitpelvdqrfalastpesltatramgksfagadfeagmmwrevyrlrqpvlliwgre
drvnpldgalvalktipraqlhvfgqcghwvqvekfdefnkltieflgggr

    Sequence, based on observed residues (ATOM records): (download) 
    >2wufB (B:)
ltfestsrfaevdvdgplklhyheagvgndqtvvllhgggpgaaswtnfsrniavlarhf
hvlavdqpgyghsdkraehgqfnryaamalkglfdqlglgrvplvgnalgggtavrfald
yparagrlvlmgpgglsinlfapdptegvkrlskfsvaptrenleaflrvmvydknlitp
elvdqrfalastpesltatramgksfagadfeagmmwrevyrlrqpvlliwgredrvnpl
dgalvalktipraqlhvfgqcghwvqvekfdefnkltieflg