PDB entry 2wu2

View 2wu2 on RCSB PDB site
Description: crystal structure of the e. coli succinate:quinone oxidoreductase (sqr) sdhc his84met mutant
Class: oxidoreductase
Keywords: cell inner membrane, tricarboxylic acid cycle, metal-binding, transmembrane, transport, flavoprotein, oxidoreductase, electron transport
Deposited on 2009-09-28, released 2010-08-25
The last revision prior to the SCOPe 2.03 freeze date was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.17876
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Succinate dehydrogenase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2a1, d2wu2a2, d2wu2a3
  • Chain 'B':
    Compound: succinate dehydrogenase iron-sulfur subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2b1, d2wu2b2
  • Chain 'C':
    Compound: succinate dehydrogenase cytochrome b556 subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P69054 (Start-128)
      • engineered mutation (83)
    Domains in SCOPe 2.03: d2wu2c_
  • Chain 'D':
    Compound: succinate dehydrogenase hydrophobic membrane anchor protein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2d_
  • Chain 'E':
    Compound: Succinate dehydrogenase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2e1, d2wu2e2, d2wu2e3
  • Chain 'F':
    Compound: succinate dehydrogenase iron-sulfur subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2f1, d2wu2f2
  • Chain 'G':
    Compound: succinate dehydrogenase cytochrome b556 subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P69054 (Start-128)
      • engineered mutation (83)
    Domains in SCOPe 2.03: d2wu2g_
  • Chain 'H':
    Compound: succinate dehydrogenase hydrophobic membrane anchor protein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2h_
  • Chain 'I':
    Compound: Succinate dehydrogenase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2i1, d2wu2i2, d2wu2i3
  • Chain 'J':
    Compound: succinate dehydrogenase iron-sulfur subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2j1, d2wu2j2
  • Chain 'K':
    Compound: succinate dehydrogenase cytochrome b556 subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P69054 (Start-128)
      • engineered mutation (83)
    Domains in SCOPe 2.03: d2wu2k_
  • Chain 'L':
    Compound: succinate dehydrogenase hydrophobic membrane anchor protein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2wu2l_
  • Heterogens: FAD, TEO, NA, FES, SF4, F3S, HEM, CBE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu2A (A:)
mklpvrefdavvigaggagmraalqisqsgqtcallskvfptrshtvsaqggitvalgnt
hednwewhmydtvkgsdyigdqdaieymcktgpeailelehmglpfsrlddgriyqrpfg
gqsknfggeqaartaaaadrtghallhtlyqqnlknhttifsewyaldlvknqdgavvgc
talcietgevvyfkaratvlatggagriyqsttnahintgdgvgmairagvpvqdmemwq
fhptgiagagvlvtegcrgeggyllnkhgerfmeryapnakdlagrdvvarsimieireg
rgcdgpwgphaklkldhlgkevlesrlpgilelsrtfahvdpvkepipviptchymmggi
ptkvtgqaltvnekgedvvvpglfavgeiacvsvhganrlggnslldlvvfgraaglhlq
esiaeqgalrdasesdveasldrlnrwnnnrngedpvairkalqecmqhnfsvfregdam
akgleqlkvirerlknarlddtssefntqrvecleldnlmetayatavsanfrtesrgah
srfdfpdrddenwlchslylpesesmtrrsvnmepklrpafppkirty

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu2B (B:)
mrlefsiyrynpdvddaprmqdytleadegrdmmlldaliqlkekdpslsfrrscregvc
gsdglnmngknglacitpisalnqpgkkivirplpglpvirdlvvdmgqfyaqyekikpy
llnngqnpparehlqmpeqrekldglyecilcaccstscpsfwwnpdkfigpagllaayr
flidsrdtetdsrldglsdafsvfrchsimncvsvcpkglnptraighiksmllqrna

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2wu2C (C:)
mirnvkkqrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeq
asaimgsffvkfimwgiltalaymvvvgirhmmmdfgyleetfeagkrsakisfvitvvl
sllagvlvw

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu2C (C:)
qrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeqasaimgs
ffvkfimwgiltalaymvvvgirhmmmdfgyleetfeagkrsakisfvitvvlsllagvl
vw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2wu2D (D:)
mvsnasalgrngvhdfilvrataivltlyiiymvgffatsgeltyevwigffasaftkvf
tllalfsilihawigmwqvltdyvkplalrlmlqlvivvalvvyviygfvvvwgv

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu2D (D:)
ngvhdfilvrataivltlyiiymvgffatsgeltyevwigffasaftkvftllalfsili
hawigmwqvltdyvkplalrlmlqlvivvalvvyviygfvvvwgv

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu2E (E:)
mklpvrefdavvigaggagmraalqisqsgqtcallskvfptrshtvsaqggitvalgnt
hednwewhmydtvkgsdyigdqdaieymcktgpeailelehmglpfsrlddgriyqrpfg
gqsknfggeqaartaaaadrtghallhtlyqqnlknhttifsewyaldlvknqdgavvgc
talcietgevvyfkaratvlatggagriyqsttnahintgdgvgmairagvpvqdmemwq
fhptgiagagvlvtegcrgeggyllnkhgerfmeryapnakdlagrdvvarsimieireg
rgcdgpwgphaklkldhlgkevlesrlpgilelsrtfahvdpvkepipviptchymmggi
ptkvtgqaltvnekgedvvvpglfavgeiacvsvhganrlggnslldlvvfgraaglhlq
esiaeqgalrdasesdveasldrlnrwnnnrngedpvairkalqecmqhnfsvfregdam
akgleqlkvirerlknarlddtssefntqrvecleldnlmetayatavsanfrtesrgah
srfdfpdrddenwlchslylpesesmtrrsvnmepklrpafppkirty

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu2F (F:)
mrlefsiyrynpdvddaprmqdytleadegrdmmlldaliqlkekdpslsfrrscregvc
gsdglnmngknglacitpisalnqpgkkivirplpglpvirdlvvdmgqfyaqyekikpy
llnngqnpparehlqmpeqrekldglyecilcaccstscpsfwwnpdkfigpagllaayr
flidsrdtetdsrldglsdafsvfrchsimncvsvcpkglnptraighiksmllqrna

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2wu2G (G:)
mirnvkkqrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeq
asaimgsffvkfimwgiltalaymvvvgirhmmmdfgyleetfeagkrsakisfvitvvl
sllagvlvw

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu2G (G:)
qrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeqasaimgs
ffvkfimwgiltalaymvvvgirhmmmdfgyleetfeagkrsakisfvitvvlsllagvl
vw

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2wu2H (H:)
mvsnasalgrngvhdfilvrataivltlyiiymvgffatsgeltyevwigffasaftkvf
tllalfsilihawigmwqvltdyvkplalrlmlqlvivvalvvyviygfvvvwgv

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu2H (H:)
ngvhdfilvrataivltlyiiymvgffatsgeltyevwigffasaftkvftllalfsili
hawigmwqvltdyvkplalrlmlqlvivvalvvyviygfvvvwgv

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu2I (I:)
mklpvrefdavvigaggagmraalqisqsgqtcallskvfptrshtvsaqggitvalgnt
hednwewhmydtvkgsdyigdqdaieymcktgpeailelehmglpfsrlddgriyqrpfg
gqsknfggeqaartaaaadrtghallhtlyqqnlknhttifsewyaldlvknqdgavvgc
talcietgevvyfkaratvlatggagriyqsttnahintgdgvgmairagvpvqdmemwq
fhptgiagagvlvtegcrgeggyllnkhgerfmeryapnakdlagrdvvarsimieireg
rgcdgpwgphaklkldhlgkevlesrlpgilelsrtfahvdpvkepipviptchymmggi
ptkvtgqaltvnekgedvvvpglfavgeiacvsvhganrlggnslldlvvfgraaglhlq
esiaeqgalrdasesdveasldrlnrwnnnrngedpvairkalqecmqhnfsvfregdam
akgleqlkvirerlknarlddtssefntqrvecleldnlmetayatavsanfrtesrgah
srfdfpdrddenwlchslylpesesmtrrsvnmepklrpafppkirty

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu2J (J:)
mrlefsiyrynpdvddaprmqdytleadegrdmmlldaliqlkekdpslsfrrscregvc
gsdglnmngknglacitpisalnqpgkkivirplpglpvirdlvvdmgqfyaqyekikpy
llnngqnpparehlqmpeqrekldglyecilcaccstscpsfwwnpdkfigpagllaayr
flidsrdtetdsrldglsdafsvfrchsimncvsvcpkglnptraighiksmllqrna

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2wu2K (K:)
mirnvkkqrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeq
asaimgsffvkfimwgiltalaymvvvgirhmmmdfgyleetfeagkrsakisfvitvvl
sllagvlvw

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu2K (K:)
qrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeqasaimgs
ffvkfimwgiltalaymvvvgirhmmmdfgyleetfeagkrsakisfvitvvlsllagvl
vw

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2wu2L (L:)
mvsnasalgrngvhdfilvrataivltlyiiymvgffatsgeltyevwigffasaftkvf
tllalfsilihawigmwqvltdyvkplalrlmlqlvivvalvvyviygfvvvwgv

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu2L (L:)
ngvhdfilvrataivltlyiiymvgffatsgeltyevwigffasaftkvftllalfsili
hawigmwqvltdyvkplalrlmlqlvivvalvvyviygfvvvwgv