PDB entry 2wtz

View 2wtz on RCSB PDB site
Description: mure ligase of mycobacterium tuberculosis
Deposited on 2009-09-25, released 2009-12-15
The last revision was dated 2011-07-13, with a file datestamp of 2011-06-02.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.19549
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2,6-diaminopimelate ligase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2,6-diaminopimelate ligase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2,6-diaminopimelate ligase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2,6-diaminopimelate ligase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: UAG, MG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2wtzA (A:)
msslargisrrrtevatqveaaptglrpnavvgvrlaaladqvgaalaegpaqravtedr
tvtgvtlraqdvspgdlfaaltgstthgarhvgdaiargavavltdpagvaeiagraavp
vlvhpaprgvlgglaatvyghpserltvigitgtsgkttttylveaglraagrvagligt
igirvggadlpsalttpeaptlqamlaamvergvdtvvmevsshalalgrvdgtrfavga
ftnlsrdhldfhpsmadyfeakaslfdpdsalrartavvcidddagramaaraadaitvs
aadrpahwratdvaptdaggqqftaidpagvghhigirlpgrynvanclvalaildtvgv
speqavpglreirvpgrleqidrgqgflalvdyahkpealrsvlttlahpdrrlavvfga
ggdrdpgkrapmgriaaqladlvvvtddnprdedptairreilagaaevggdaqvveiad
rrdairhavawarpgdvvliagkghetgqrgggrvrpfddrvelaaalealerra

    Sequence, based on observed residues (ATOM records):
    >2wtzA (A:)
lrpnavvgvrlaaladqvgaalaegpravtedrtvtgvtlraqdvspgdlfaaltgstth
garhvgdaiargavavltdpagvaeiagraavpvlvhpaprgvlgglaatvyghpserlt
vigitgtsgkttttylveaglraagrvagligtigirvggadlpsalttpeaptlqamla
amvergvdtvvmevsshalalgrvdgtrfavgaftnlsrdhldfhpsmadyfeakaslfd
pdsalrartavvcidddagramaaraadaitvsaadrpahwratdvaptdaggqqftaid
pagvghhigirlpgrynvanclvalaildtvgvspeqavpglreirvpgrleqidrgqgf
lalvdyahkpealrsvlttlahpdrrlavvfgaggdrdpgkrapmgriaaqladlvvvtd
dnprdedptairreilagaaevgdaqvveiadrrdairhavawarpgdvvliagkghetg
qrggrvrpfddrvelaaalealer

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wtzB (B:)
msslargisrrrtevatqveaaptglrpnavvgvrlaaladqvgaalaegpaqravtedr
tvtgvtlraqdvspgdlfaaltgstthgarhvgdaiargavavltdpagvaeiagraavp
vlvhpaprgvlgglaatvyghpserltvigitgtsgkttttylveaglraagrvagligt
igirvggadlpsalttpeaptlqamlaamvergvdtvvmevsshalalgrvdgtrfavga
ftnlsrdhldfhpsmadyfeakaslfdpdsalrartavvcidddagramaaraadaitvs
aadrpahwratdvaptdaggqqftaidpagvghhigirlpgrynvanclvalaildtvgv
speqavpglreirvpgrleqidrgqgflalvdyahkpealrsvlttlahpdrrlavvfga
ggdrdpgkrapmgriaaqladlvvvtddnprdedptairreilagaaevggdaqvveiad
rrdairhavawarpgdvvliagkghetgqrgggrvrpfddrvelaaalealerra

    Sequence, based on observed residues (ATOM records):
    >2wtzB (B:)
lrpnavvgvrlaaladqvgaalaegpaqravtedrtvtgvtlraqdvspgdlfaaltgst
thgarhvgdaiargavavltdpagvaeiagraavpvlvhpaprgvlgglaatvyghpser
ltvigitgtsgkttttylveaglraagrvagligtigirvggadlpsalttpeaptlqam
laamvergvdtvvmevsshalalgrvdgtrfavgaftnlsrdhldfhpsmadyfeakasl
fdpdsalrartavvcidddagramaaraadaitvsaadrpahwratdvaptdaggqqfta
idpagvghhigirlpgrynvanclvalaildtvgvspeqavpglreirvpgrleqidrgq
gflalvdyahkpealrsvlttlahpdrrlavvfgaggdrdpgkrapmgriaaqladlvvv
tddnprdedptairreilagaaevggdaqvveiadrrdairhavawarpgdvvliagkgh
etgqrgggrvrpfddrvelaaalealer

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2wtzC (C:)
msslargisrrrtevatqveaaptglrpnavvgvrlaaladqvgaalaegpaqravtedr
tvtgvtlraqdvspgdlfaaltgstthgarhvgdaiargavavltdpagvaeiagraavp
vlvhpaprgvlgglaatvyghpserltvigitgtsgkttttylveaglraagrvagligt
igirvggadlpsalttpeaptlqamlaamvergvdtvvmevsshalalgrvdgtrfavga
ftnlsrdhldfhpsmadyfeakaslfdpdsalrartavvcidddagramaaraadaitvs
aadrpahwratdvaptdaggqqftaidpagvghhigirlpgrynvanclvalaildtvgv
speqavpglreirvpgrleqidrgqgflalvdyahkpealrsvlttlahpdrrlavvfga
ggdrdpgkrapmgriaaqladlvvvtddnprdedptairreilagaaevggdaqvveiad
rrdairhavawarpgdvvliagkghetgqrgggrvrpfddrvelaaalealerra

    Sequence, based on observed residues (ATOM records):
    >2wtzC (C:)
tglrpnavvgvrlaaladqvgaalaegvtedrtvtgvtlraqdvspgdlfaaltgstthg
arhvgdaiargavavltdpagvaeiagraavpvlvhpaprgvlgglaatvyghpserltv
igitgtsgkttttylveaglraagrvagligtigirvggadlpsalttpeaptlqamlaa
mvergvdtvvmevsshalalgrvdgtrfavgaftnlsrdhldfhpsmadyfeakaslfdp
dsalrartavvcidddagramaaraadaitvsaadrpahwratdvaptdaggqqftaidp
agvghhigirlpgrynvanclvalaildtvgvspeqavpglreirvpgrleqgflalvdy
ahkpealrsvlttlahrlavvfrapmgriadlvvvtdptairreilaqvveiadrrdair
havawarpgdvvliagkgh

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2wtzD (D:)
msslargisrrrtevatqveaaptglrpnavvgvrlaaladqvgaalaegpaqravtedr
tvtgvtlraqdvspgdlfaaltgstthgarhvgdaiargavavltdpagvaeiagraavp
vlvhpaprgvlgglaatvyghpserltvigitgtsgkttttylveaglraagrvagligt
igirvggadlpsalttpeaptlqamlaamvergvdtvvmevsshalalgrvdgtrfavga
ftnlsrdhldfhpsmadyfeakaslfdpdsalrartavvcidddagramaaraadaitvs
aadrpahwratdvaptdaggqqftaidpagvghhigirlpgrynvanclvalaildtvgv
speqavpglreirvpgrleqidrgqgflalvdyahkpealrsvlttlahpdrrlavvfga
ggdrdpgkrapmgriaaqladlvvvtddnprdedptairreilagaaevggdaqvveiad
rrdairhavawarpgdvvliagkghetgqrgggrvrpfddrvelaaalealerra

    Sequence, based on observed residues (ATOM records):
    >2wtzD (D:)
lrpnavvgvrlaaladqvgaalaegpaqravtedrtvtgvtlraqdvspgdlfaaltgst
thgarhvgdaiargavavltdpagvaeiagraavpvlvhpaprgvlgglaatvyghpser
ltvigitgtsgkttttylveaglraagrvagligtigirvggadlpsalttpeaptlqam
laamvergvdtvvmevsshalalgrvdgtrfavgaftnlsrdhldfhpsmadyfeakasl
fdpdsalrartavvcidddagramaaraadaitvsaadrpahwratdvaptdaggqqfta
idpagvghhigirlpgrynvanclvalaildtvgvspeqavpglreirvpgrleqilalv
dyahkpealrsvlttlavvfgaggdrdpgkrapmgriaaqladlvvvtddnprdedptad
aqvveiadrrdairhavawarpgdvvliagkghetgqrfddrvelaaa