PDB entry 2wtx

View 2wtx on RCSB PDB site
Description: insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase
Class: transferase
Keywords: trehalose synthase, glycosyltransferase, potassium, retention, transferase, stress response
Deposited on 2009-09-25, released 2010-02-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-02-23, with a file datestamp of 2010-02-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.19698
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha, alpha-trehalose-phosphate synthase [udp-forming]
    Species: Escherichia coli [TaxId:83333]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wtxa_
  • Chain 'B':
    Compound: alpha, alpha-trehalose-phosphate synthase [udp-forming]
    Species: Escherichia coli [TaxId:83333]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wtxb_
  • Chain 'C':
    Compound: alpha, alpha-trehalose-phosphate synthase [udp-forming]
    Species: Escherichia coli [TaxId:83333]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wtxc_
  • Chain 'D':
    Compound: alpha, alpha-trehalose-phosphate synthase [udp-forming]
    Species: Escherichia coli [TaxId:83333]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wtxd_
  • Heterogens: EDO, UDP, VDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wtxA (A:)
msrlvvvsnriappdehaasagglavgilgalkaagglwfgwsgetgnedqplkkvkkgn
itwasfnlseqdldeyynqfsnavlwpafhyrldlvqfqrpawdgylrvnalladkllpl
lqdddiiwihdyhllpfahelrkrgvnnrigfflhipfptpeifnalptydtlleqlcdy
dllgfqtendrlafldclsnltrvttrsakshtawgkafrtevypigiepkeiakqaagp
lppklaqlkaelknvqnifsverldyskglperflayeallekypqhhgkirytqiapts
rgdvqayqdirhqleneagringkygqlgwtplyylnqhfdrkllmkifrysdvglvtpl
rdgmnlvakeyvaaqdpanpgvlvlsqfagaaneltsalivnpydrdevaaaldraltms
laerisrhaemldvivkndinhwqecfisdlkqivprsaesqqrdkvatfpkla

    Sequence, based on observed residues (ATOM records): (download) 
    >2wtxA (A:)
srlvvvsnriappdehaasagglavgilgalkaagglwfgwsgetgnedqplkkvkkgni
twasfnlseqdldeyynqfsnavlwpafhyrldlvqfqrpawdgylrvnalladkllpll
qdddiiwihdyhllpfahelrkrgvnnrigfflhipfptpeifnalptydtlleqlcdyd
llgfqtendrlafldclsnltrvttrsakshtawgkafrtevypigiepkeiakqaagpl
ppklaqlkaelknvqnifsverldyskglperflayeallekypqhhgkirytqiaptsr
gdvqayqdirhqleneagringkygqlgwtplyylnqhfdrkllmkifrysdvglvtplr
dgmnlvakeyvaaqdpanpgvlvlsqfagaaneltsalivnpydrdevaaaldraltmsl
aerisrhaemldvivkndinhwqecfisdlkqivpr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wtxB (B:)
msrlvvvsnriappdehaasagglavgilgalkaagglwfgwsgetgnedqplkkvkkgn
itwasfnlseqdldeyynqfsnavlwpafhyrldlvqfqrpawdgylrvnalladkllpl
lqdddiiwihdyhllpfahelrkrgvnnrigfflhipfptpeifnalptydtlleqlcdy
dllgfqtendrlafldclsnltrvttrsakshtawgkafrtevypigiepkeiakqaagp
lppklaqlkaelknvqnifsverldyskglperflayeallekypqhhgkirytqiapts
rgdvqayqdirhqleneagringkygqlgwtplyylnqhfdrkllmkifrysdvglvtpl
rdgmnlvakeyvaaqdpanpgvlvlsqfagaaneltsalivnpydrdevaaaldraltms
laerisrhaemldvivkndinhwqecfisdlkqivprsaesqqrdkvatfpkla

    Sequence, based on observed residues (ATOM records): (download) 
    >2wtxB (B:)
srlvvvsnriappdsagglavgilgalkaagglwfgwsgetgnedqplkkvkkgnitwas
fnlseqdldeyynqfsnavlwpafhyrldlvqfqrpawdgylrvnalladkllpllqddd
iiwihdyhllpfahelrkrgvnnrigfflhipfptpeifnalptydtlleqlcdydllgf
qtendrlafldclsnltrvttrsakshtawgkafrtevypigiepkeiakqaagplppkl
aqlkaelknvqnifsverldyskglperflayeallekypqhhgkirytqiaptsrgdvq
ayqdirhqleneagringkygqlgwtplyylnqhfdrkllmkifrysdvglvtplrdgmn
lvakeyvaaqdpanpgvlvlsqfagaaneltsalivnpydrdevaaaldraltmslaeri
srhaemldvivkndinhwqecfisdlkqivprsa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2wtxC (C:)
msrlvvvsnriappdehaasagglavgilgalkaagglwfgwsgetgnedqplkkvkkgn
itwasfnlseqdldeyynqfsnavlwpafhyrldlvqfqrpawdgylrvnalladkllpl
lqdddiiwihdyhllpfahelrkrgvnnrigfflhipfptpeifnalptydtlleqlcdy
dllgfqtendrlafldclsnltrvttrsakshtawgkafrtevypigiepkeiakqaagp
lppklaqlkaelknvqnifsverldyskglperflayeallekypqhhgkirytqiapts
rgdvqayqdirhqleneagringkygqlgwtplyylnqhfdrkllmkifrysdvglvtpl
rdgmnlvakeyvaaqdpanpgvlvlsqfagaaneltsalivnpydrdevaaaldraltms
laerisrhaemldvivkndinhwqecfisdlkqivprsaesqqrdkvatfpkla

    Sequence, based on observed residues (ATOM records): (download) 
    >2wtxC (C:)
srlvvvsnriapglavgilgalkaagglwfgwsgetgnqplkkvkkgnitwasfnlseqd
ldeyynqfsnavlwpafhyrldlvqfqrpawdgylrvnalladkllpllqdddiiwihdy
hllpfahelrkrgvnnrigfflhipfptpeifnalptydtlleqlcdydllgfqtendrl
afldclsnltrvttrsakshtawgkafrtevypigiepkeiakqaagpaqlkaelknvqn
ifsverldyskglperflayeallekypqhhgkirytqiaptsrgdvqayqdirhqlene
agringkygqlgwtplyylnqhfdrkllmkifrysdvglvtplrdgmnlvakeyvaaqdp
anpgvlvlsqfagaaneltsalivnpydrdevaaaldraltmslaerisrhaemldvivk
ndinhwqecfisdlkqivpr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2wtxD (D:)
msrlvvvsnriappdehaasagglavgilgalkaagglwfgwsgetgnedqplkkvkkgn
itwasfnlseqdldeyynqfsnavlwpafhyrldlvqfqrpawdgylrvnalladkllpl
lqdddiiwihdyhllpfahelrkrgvnnrigfflhipfptpeifnalptydtlleqlcdy
dllgfqtendrlafldclsnltrvttrsakshtawgkafrtevypigiepkeiakqaagp
lppklaqlkaelknvqnifsverldyskglperflayeallekypqhhgkirytqiapts
rgdvqayqdirhqleneagringkygqlgwtplyylnqhfdrkllmkifrysdvglvtpl
rdgmnlvakeyvaaqdpanpgvlvlsqfagaaneltsalivnpydrdevaaaldraltms
laerisrhaemldvivkndinhwqecfisdlkqivprsaesqqrdkvatfpkla

    Sequence, based on observed residues (ATOM records): (download) 
    >2wtxD (D:)
srlvvvsnriappdehaasagglavgilgalkaagglwfgwsgetgnedqplkkvkkgni
twasfnlseqdldeyynqfsnavlwpafhyrldlvqfqrpawdgylrvnalladkllpll
qdddiiwihdyhllpfahelrkrgvnnrigfflhipfptpeifnalptydtlleqlcdyd
llgfqtendrlafldclsnltrvttrsakshtawgkafrtevypigiepkeiakqaagpl
ppklaqlkaelknvqnifsverldyskglperflayeallekypqhhgkirytqiaptsr
gdvqayqdirhqleneagringkygqlgwtplyylnqhfdrkllmkifrysdvglvtplr
dgmnlvakeyvaaqdpanpgvlvlsqfagaaneltsalivnpydrdevaaaldraltmsl
aerisrhaemldvivkndinhwqecfisdlkqivprs