PDB entry 2ws7

View 2ws7 on RCSB PDB site
Description: Semi-synthetic analogue of human insulin ProB26-DTI
Deposited on 2009-09-03, released 2010-02-09
The last revision was dated 2012-06-06, with a file datestamp of 2012-06-01.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: 0.21386
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin A chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: insulin B chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: insulin A chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: insulin B chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: insulin A chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: insulin B chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: insulin A chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: insulin B chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01308 (0-25)
      • engineered mutation (25)
  • Chain 'I':
    Compound: insulin A chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: insulin B chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: insulin A chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: insulin B chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: IPH, ZN, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2ws7A (A:)
giveqcctsicslyqlenycn

    Sequence, based on observed residues (ATOM records):
    >2ws7A (A:)
iveqcctsicslyqlenycn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2ws7B (B:)
fvnqhlcgshlvealylvcgergffp

    Sequence, based on observed residues (ATOM records):
    >2ws7B (B:)
fvnqhlcgshlvealylvc

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >2ws7C (C:)
giveqcctsicslyqlenycn

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2ws7D (D:)
fvnqhlcgshlvealylvcgergffp

    Sequence, based on observed residues (ATOM records):
    >2ws7D (D:)
fvnqhlcgshlvealylvcgerg

  • Chain 'E':
    Sequence, based on SEQRES records:
    >2ws7E (E:)
giveqcctsicslyqlenycn

    Sequence, based on observed residues (ATOM records):
    >2ws7E (E:)
giveqcctsicslyqlenyc

  • Chain 'F':
    Sequence, based on SEQRES records:
    >2ws7F (F:)
fvnqhlcgshlvealylvcgergffp

    Sequence, based on observed residues (ATOM records):
    >2ws7F (F:)
fvnqhlcgshlvealylvcg

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >2ws7G (G:)
giveqcctsicslyqlenycn

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >2ws7H (H:)
fvnqhlcgshlvealylvcgergffp

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >2ws7I (I:)
giveqcctsicslyqlenycn

  • Chain 'J':
    Sequence, based on SEQRES records:
    >2ws7J (J:)
fvnqhlcgshlvealylvcgergffp

    Sequence, based on observed residues (ATOM records):
    >2ws7J (J:)
fvnqhlcgshlvealylvcge

  • Chain 'K':
    Sequence, based on SEQRES records:
    >2ws7K (K:)
giveqcctsicslyqlenycn

    Sequence, based on observed residues (ATOM records):
    >2ws7K (K:)
iveqcctsicslyqlenyc

  • Chain 'L':
    Sequence, based on SEQRES records:
    >2ws7L (L:)
fvnqhlcgshlvealylvcgergffp

    Sequence, based on observed residues (ATOM records):
    >2ws7L (L:)
vnqhlcgshlvealylvcger