PDB entry 2wrw

View 2wrw on RCSB PDB site
Description: Semi-synthetic highly active analogue of human insulin D-ProB26-DTI- NH2
Deposited on 2009-09-02, released 2010-02-09
The last revision was dated 2012-06-06, with a file datestamp of 2012-06-01.
Experiment type: XRAY
Resolution: 2.41 Å
R-factor: 0.23931
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin A chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: insulin B chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01308 (Start-25)
      • engineered mutation (25)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >2wrwA (A:)
giveqcctsicslyqlenycn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wrwB (B:)
fvnqhlcgshlvealylvcgergffx

    Sequence, based on observed residues (ATOM records):
    >2wrwB (B:)
vnqhlcgshlvealylvcgergffx