PDB entry 2wrv

View 2wrv on RCSB PDB site
Description: semi-synthetic highly active analogue of human insulin nmehisb26-dti- nh2
Deposited on 2009-09-02, released 2010-02-09
The last revision was dated 2017-08-30, with a file datestamp of 2017-08-25.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin A chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: insulin B chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01308 (Start-25)
      • engineered mutation (25)
  • Heterogens: ACT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >2wrvA (A:)
    giveqcctsicslyqlenycn
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wrvB (B:)
    fvnqhlcgshlvealylvcgergffx
    

    Sequence, based on observed residues (ATOM records):
    >2wrvB (B:)
    vnqhlcgshlvealylvcgergffx