PDB entry 2wqa
View 2wqa on RCSB PDB site
Description: complex of ttr and rbp4 and oleic acid
Class: hydrolase/signaling protein
Keywords: hydrolase-signaling protein complex, thyroid hormone, retinol-binding, disease mutation, sensory transduction, vitamin a, neuropathy, amyloidosis, vision, hormone, amyloid
Deposited on
2009-08-14, released
2010-09-01
The last revision prior to the SCOPe 2.06 freeze date was dated
2010-09-01, with a file datestamp of
2010-08-27.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.2279
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2wqaa_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2wqab_ - Chain 'C':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2wqac_ - Chain 'D':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2wqad_ - Chain 'E':
Compound: retinol-binding protein 4
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2wqae_ - Chain 'F':
Compound: retinol-binding protein 4
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2wqaf_ - Heterogens: SO4, OLA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2wqaA (A:)
gsgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgl
tteeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysyst
tavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>2wqaA (A:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2wqaB (B:)
gsgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgl
tteeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysyst
tavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>2wqaB (B:)
gkcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefveg
iykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2wqaC (C:)
gsgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgl
tteeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysyst
tavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>2wqaC (C:)
gtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteee
fvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvt
n
- Chain 'D':
Sequence, based on SEQRES records: (download)
>2wqaD (D:)
gsgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgl
tteeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysyst
tavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>2wqaD (D:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
- Chain 'E':
Sequence, based on SEQRES records: (download)
>2wqaE (E:)
gerdcrvssfrvkenfdkarfsgtwyamakkdpeglflqdnivaefsvdetgqmsatakg
rvrllnnwdvcadmvgtftdtedpakfkmkywgvasflqkgnddhwivdtdydtyavqys
crllnldgtcadsysfvfsrdpnglppeaqkivrqrqeelclarqyrlivhngycdg
Sequence, based on observed residues (ATOM records): (download)
>2wqaE (E:)
erdcrvssfrvkenfdkarfsgtwyamakkdpeglflqdnivaefsvdetgqmsatakgr
vrllnnwdvcadmvgtftdtedpakfkmkywgvasflqkgnddhwivdtdydtyavqysc
rllnldgtcadsysfvfsrdpnglppeaqkivrqrqeelclarqyrlivhngycdg
- Chain 'F':
Sequence, based on SEQRES records: (download)
>2wqaF (F:)
gerdcrvssfrvkenfdkarfsgtwyamakkdpeglflqdnivaefsvdetgqmsatakg
rvrllnnwdvcadmvgtftdtedpakfkmkywgvasflqkgnddhwivdtdydtyavqys
crllnldgtcadsysfvfsrdpnglppeaqkivrqrqeelclarqyrlivhngycdg
Sequence, based on observed residues (ATOM records): (download)
>2wqaF (F:)
erdcrvssfrvkenfdkarfsgtwyamakkdpeglflqdnivaefsvdetgqmsatakgr
vrllnnwdvcadmvgtftdtedpakfkmkywgvasflqkgnddhwivdtdydtyavqysc
rllnldgtcadsysfvfsrdpnglppeaqkivrqrqeelclarqyrlivhngycdg