PDB entry 2wpo

View 2wpo on RCSB PDB site
Description: HCMV protease inhibitor complex
Class: hydrolase/hydrolase inhibitor
Keywords: VIRAL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR complex, COAT PROTEIN, SERINE PROTEASE
Deposited on 1998-08-04, released 1999-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-07-07.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.226
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: human cytomegalovirus protease
    Species: Human herpesvirus 5 [TaxId:10359]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16753 (Start-255)
      • engineered (142)
      • engineered (180)
      • engineered (228)
    Domains in SCOPe 2.08: d2wpoa_
  • Chain 'B':
    Compound: human cytomegalovirus protease
    Species: Human herpesvirus 5 [TaxId:10359]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16753 (Start-255)
      • engineered (142)
      • engineered (180)
      • engineered (228)
    Domains in SCOPe 2.08: d2wpob_
  • Chain 'C':
    Compound: human cytomegalovirus protease
    Species: Human herpesvirus 5 [TaxId:10359]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16753 (Start-255)
      • engineered (142)
      • engineered (180)
      • engineered (228)
    Domains in SCOPe 2.08: d2wpoc_
  • Chain 'D':
    Compound: human cytomegalovirus protease
    Species: Human herpesvirus 5 [TaxId:10359]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16753 (Start-255)
      • engineered (142)
      • engineered (180)
      • engineered (228)
    Domains in SCOPe 2.08: d2wpod_
  • Heterogens: 01E

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wpoA (A:)
mtmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqgqgqpslsvalpln
inhddtavvghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkv
veflsgsyaglslssrrcddveqatslsgsettpfkhvalcsvgrrrgtlavygrdpewv
mqrfpdltaadrdglraqwqrcgstavdasgdpfrsdsygllgnsvdamyirerlpklry
dkqlvgvteresyvka

    Sequence, based on observed residues (ATOM records): (download) 
    >2wpoA (A:)
deqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqlsvalplninhddtavv
ghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkvveflsgsya
glslssrrcddveqttpfkhvalcsvgrrrgtlavygrdpewvmqrfpdltaadrdglra
qwqsgdpfrsdsygllgnsvdamyirerlpklrydkqlvgvteresyvka

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wpoB (B:)
mtmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqgqgqpslsvalpln
inhddtavvghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkv
veflsgsyaglslssrrcddveqatslsgsettpfkhvalcsvgrrrgtlavygrdpewv
mqrfpdltaadrdglraqwqrcgstavdasgdpfrsdsygllgnsvdamyirerlpklry
dkqlvgvteresyvka

    Sequence, based on observed residues (ATOM records): (download) 
    >2wpoB (B:)
deqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqlsvalplninhddtavv
ghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkvveflsgsya
glslssrrcddveqttpfkhvalcsvgrrrgtlavygrdpewvmqrfpdltaadrdglra
qwqsgdpfrsdsygllgnsvdamyirerlpklrydkqlvgvteresyvka

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2wpoC (C:)
mtmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqgqgqpslsvalpln
inhddtavvghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkv
veflsgsyaglslssrrcddveqatslsgsettpfkhvalcsvgrrrgtlavygrdpewv
mqrfpdltaadrdglraqwqrcgstavdasgdpfrsdsygllgnsvdamyirerlpklry
dkqlvgvteresyvka

    Sequence, based on observed residues (ATOM records): (download) 
    >2wpoC (C:)
deqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqlsvalplninhddtavv
ghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkvveflsgsya
glslssrrcddveqttpfkhvalcsvgrrrgtlavygrdpewvmqrfpdltaadrdglra
qwqsgdpfrsdsygllgnsvdamyirerlpklrydkqlvgvteresyvka

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2wpoD (D:)
mtmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqgqgqpslsvalpln
inhddtavvghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkv
veflsgsyaglslssrrcddveqatslsgsettpfkhvalcsvgrrrgtlavygrdpewv
mqrfpdltaadrdglraqwqrcgstavdasgdpfrsdsygllgnsvdamyirerlpklry
dkqlvgvteresyvka

    Sequence, based on observed residues (ATOM records): (download) 
    >2wpoD (D:)
deqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqlsvalplninhddtavv
ghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkvveflsgsya
glslssrrcddveqttpfkhvalcsvgrrrgtlavygrdpewvmqrfpdltaadrdglra
qwqsgdpfrsdsygllgnsvdamyirerlpklrydkqlvgvteresyvka