PDB entry 2wov

View 2wov on RCSB PDB site
Description: trypanosoma brucei trypanothione reductase with bound nadp.
Deposited on 2009-07-30, released 2010-08-04
The last revision was dated 2017-06-28, with a file datestamp of 2017-06-23.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: trypanothione reductase
    Species: TRYPANOSOMA BRUCEI [TaxId:185431]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q389T8 (3-End)
      • expression tag (1-2)
  • Chain 'B':
    Compound: trypanothione reductase
    Species: TRYPANOSOMA BRUCEI [TaxId:185431]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: trypanothione reductase
    Species: TRYPANOSOMA BRUCEI [TaxId:185431]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q389T8 (3-End)
      • expression tag (1-2)
  • Chain 'D':
    Compound: trypanothione reductase
    Species: TRYPANOSOMA BRUCEI [TaxId:185431]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NDP, FAD, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2wovA (A:)
gshmskafdlvvigagsggleagwnaatlygkrvavvdvqtshgppfyaalggtcvnvgc
vpkklmvtgaqymdhlresagfgwefdgssvkanwkkliaakneavldinksyegmfndt
egldfflgwgslesknvvvvretadpksavkerlqadhillatgswpqmpaipgiehcis
sneafylpepprrvltvgggfisvefagifnaykppggkvtlcyrnnlilrgfdetiree
vtkqltangieimtnenpakvslntdgskhvtfesgktldvdvvmmaigriprtndlqlg
nvgvkltpkggvqvdefsrtnvpniyaigditdrlmltpvainegaalvdtvfgnkprkt
dhtrvasavfsippigtcglieevaakefekvavymssftplmhnisgskykkfvakivt
nhsdgtvlgvhllgdgapeiiqavgvclrlnakisdfyntigvhptsaeelcsmrtpsyy
yvkgekmeklpdsnl

    Sequence, based on observed residues (ATOM records):
    >2wovA (A:)
shmskafdlvvigagsggleagwnaatlygkrvavvdvqtshgppfyaalggtcvnvgcv
pkklmvtgaqymdhlresagfgwefdgssvkanwkkliaakneavldinksyegmfndte
gldfflgwgslesknvvvvretadpksavkerlqadhillatgswpqmpaipgiehciss
neafylpepprrvltvgggfisvefagifnaykppggkvtlcyrnnlilrgfdetireev
tkqltangieimtnenpakvslntdgskhvtfesgktldvdvvmmaigriprtndlqlgn
vgvkltpkggvqvdefsrtnvpniyaigditdrlmltpvainegaalvdtvfgnkprktd
htrvasavfsippigtcglieevaakefekvavymssftplmhnisgskykkfvakivtn
hsdgtvlgvhllgdgapeiiqavgvclrlnakisdfyntigvhptsaeelcsmrtpsyyy
vkgekmeklp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wovB (B:)
gshmskafdlvvigagsggleagwnaatlygkrvavvdvqtshgppfyaalggtcvnvgc
vpkklmvtgaqymdhlresagfgwefdgssvkanwkkliaakneavldinksyegmfndt
egldfflgwgslesknvvvvretadpksavkerlqadhillatgswpqmpaipgiehcis
sneafylpepprrvltvgggfisvefagifnaykppggkvtlcyrnnlilrgfdetiree
vtkqltangieimtnenpakvslntdgskhvtfesgktldvdvvmmaigriprtndlqlg
nvgvkltpkggvqvdefsrtnvpniyaigditdrlmltpvainegaalvdtvfgnkprkt
dhtrvasavfsippigtcglieevaakefekvavymssftplmhnisgskykkfvakivt
nhsdgtvlgvhllgdgapeiiqavgvclrlnakisdfyntigvhptsaeelcsmrtpsyy
yvkgekmeklpdsnl

    Sequence, based on observed residues (ATOM records):
    >2wovB (B:)
skafdlvvigagsggleagwnaatlygkrvavvdvqtshgppfyaalggtcvnvgcvpkk
lmvtgaqymdhlresagfgwefdgssvkanwkkliaakneavldinksyegmfndtegld
fflgwgslesknvvvvretadpksavkerlqadhillatgswpqmpaipgiehcissnea
fylpepprrvltvgggfisvefagifnaykppggkvtlcyrnnlilrgfdetireevtkq
ltangieimtnenpakvslntdgskhvtfesgktldvdvvmmaigriprtndlqlgnvgv
kltpkggvqvdefsrtnvpniyaigditdrlmltpvainegaalvdtvfgnkprktdhtr
vasavfsippigtcglieevaakefekvavymssftplmhnisgskykkfvakivtnhsd
gtvlgvhllgdgapeiiqavgvclrlnakisdfyntigvhptsaeelcsmrtpsyyyvkg
ekmekl

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2wovC (C:)
gshmskafdlvvigagsggleagwnaatlygkrvavvdvqtshgppfyaalggtcvnvgc
vpkklmvtgaqymdhlresagfgwefdgssvkanwkkliaakneavldinksyegmfndt
egldfflgwgslesknvvvvretadpksavkerlqadhillatgswpqmpaipgiehcis
sneafylpepprrvltvgggfisvefagifnaykppggkvtlcyrnnlilrgfdetiree
vtkqltangieimtnenpakvslntdgskhvtfesgktldvdvvmmaigriprtndlqlg
nvgvkltpkggvqvdefsrtnvpniyaigditdrlmltpvainegaalvdtvfgnkprkt
dhtrvasavfsippigtcglieevaakefekvavymssftplmhnisgskykkfvakivt
nhsdgtvlgvhllgdgapeiiqavgvclrlnakisdfyntigvhptsaeelcsmrtpsyy
yvkgekmeklpdsnl

    Sequence, based on observed residues (ATOM records):
    >2wovC (C:)
shmskafdlvvigagsggleagwnaatlygkrvavvdvqtshgppfyaalggtcvnvgcv
pkklmvtgaqymdhlresagfgwefdgssvkanwkkliaakneavldinksyegmfndte
gldfflgwgslesknvvvvretadpksavkerlqadhillatgswpqmpaipgiehciss
neafylpepprrvltvgggfisvefagifnaykppggkvtlcyrnnlilrgfdetireev
tkqltangieimtnenpakvslntdgskhvtfesgktldvdvvmmaigriprtndlqlgn
vgvkltpkggvqvdefsrtnvpniyaigditdrlmltpvainegaalvdtvfgnkprktd
htrvasavfsippigtcglieevaakefekvavymssftplmhnisgskykkfvakivtn
hsdgtvlgvhllgdgapeiiqavgvclrlnakisdfyntigvhptsaeelcsmrtpsyyy
vkgekmeklp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2wovD (D:)
gshmskafdlvvigagsggleagwnaatlygkrvavvdvqtshgppfyaalggtcvnvgc
vpkklmvtgaqymdhlresagfgwefdgssvkanwkkliaakneavldinksyegmfndt
egldfflgwgslesknvvvvretadpksavkerlqadhillatgswpqmpaipgiehcis
sneafylpepprrvltvgggfisvefagifnaykppggkvtlcyrnnlilrgfdetiree
vtkqltangieimtnenpakvslntdgskhvtfesgktldvdvvmmaigriprtndlqlg
nvgvkltpkggvqvdefsrtnvpniyaigditdrlmltpvainegaalvdtvfgnkprkt
dhtrvasavfsippigtcglieevaakefekvavymssftplmhnisgskykkfvakivt
nhsdgtvlgvhllgdgapeiiqavgvclrlnakisdfyntigvhptsaeelcsmrtpsyy
yvkgekmeklpdsnl

    Sequence, based on observed residues (ATOM records):
    >2wovD (D:)
skafdlvvigagsggleagwnaatlygkrvavvdvqtshgppfyaalggtcvnvgcvpkk
lmvtgaqymdhlresagfgwefdgssvkanwkkliaakneavldinksyegmfndtegld
fflgwgslesknvvvvretadpksavkerlqadhillatgswpqmpaipgiehcissnea
fylpepprrvltvgggfisvefagifnaykppggkvtlcyrnnlilrgfdetireevtkq
ltangieimtnenpakvslntdgskhvtfesgktldvdvvmmaigriprtndlqlgnvgv
kltpkggvqvdefsrtnvpniyaigditdrlmltpvainegaalvdtvfgnkprktdhtr
vasavfsippigtcglieevaakefekvavymssftplmhnisgskykkfvakivtnhsd
gtvlgvhllgdgapeiiqavgvclrlnakisdfyntigvhptsaeelcsmrtpsyyyvkg
ekmeklp