PDB entry 2wo6

View 2wo6 on RCSB PDB site
Description: human dual-specificity tyrosine-phosphorylation-regulated kinase 1a in complex with a consensus substrate peptide
Deposited on 2009-07-22, released 2009-08-18
The last revision was dated 2016-12-21, with a file datestamp of 2016-12-16.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dual specificity tyrosine-phosphorylation- regulated kinase 1a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: dual specificity tyrosine-phosphorylation- regulated kinase 1a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: artificial consensus sequence
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WO6 (0-7)
  • Heterogens: D15, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2wo6A (A:)
    mhhhhhhssgvdlgtenlyfqsmsshkkerkvyndgydddnydyivkngekwmdryeids
    ligkgsfgqvvkaydrveqewvaikiiknkkaflnqaqievrllelmnkhdtemkyyivh
    lkrhfmfrnhlclvfemlsynlydllrntnfrgvslnltrkfaqqmctallflatpelsi
    ihcdlkpenillcnpkrsaikivdfgsscqlgqriyqyiqsrfyrspevllgmpydlaid
    mwslgcilvemhtgeplfsganevdqmnkivevlgippahildqapkarkffeklpdgtw
    nlkktkdgkreykppgtrklhnilgvetggpggrragesghtvadylkfkdlilrmldyd
    pktriqpyyalqhsffkktade
    

    Sequence, based on observed residues (ATOM records):
    >2wo6A (A:)
    rkvyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveqewvaikiikn
    kkaflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemlsynlydllrnt
    nfrgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsaikivdfgssc
    qlgqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfsganevdqmnk
    ivevlgippahildqapkarkffeklpdgtwnlkktreykppgtrklhnilgvetggpgg
    rragesghtvadylkfkdlilrmldydpktriqpyyalqhsffkk
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wo6B (B:)
    mhhhhhhssgvdlgtenlyfqsmsshkkerkvyndgydddnydyivkngekwmdryeids
    ligkgsfgqvvkaydrveqewvaikiiknkkaflnqaqievrllelmnkhdtemkyyivh
    lkrhfmfrnhlclvfemlsynlydllrntnfrgvslnltrkfaqqmctallflatpelsi
    ihcdlkpenillcnpkrsaikivdfgsscqlgqriyqyiqsrfyrspevllgmpydlaid
    mwslgcilvemhtgeplfsganevdqmnkivevlgippahildqapkarkffeklpdgtw
    nlkktkdgkreykppgtrklhnilgvetggpggrragesghtvadylkfkdlilrmldyd
    pktriqpyyalqhsffkktade
    

    Sequence, based on observed residues (ATOM records):
    >2wo6B (B:)
    yndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveqewvaikiiknkka
    flnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemlsynlydllrntnfr
    gvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsaikivdfgsscqlg
    qriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfsganevdqmnkive
    vlgippahildqapkarkffeklpdgtwnlkkreykppgtrklhnilgvetggpggrrag
    esghtvadylkfkdlilrmldydpktriqpyyalqhsffk
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >2wo6C (C:)
    arpgtpal