PDB entry 2wo3

View 2wo3 on RCSB PDB site
Description: crystal structure of the epha4-ephrina2 complex
Class: transferase/signaling protein
Keywords: transferase-signaling protein complex, efn, eph, epha4, kinase, ephrin, complex, membrane, cell surface receptor, tyrosine-protein kinase, glycoprotein, ephrina2
Deposited on 2009-07-21, released 2009-10-27
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-11-23, with a file datestamp of 2011-11-18.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.20012
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ephrin type-a receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54764 (3-175)
      • expression tag (1-2)
      • expression tag (176)
    Domains in SCOPe 2.04: d2wo3a_
  • Chain 'B':
    Compound: ephrin-a2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43921 (3-143)
      • engineered mutation (144)
    Domains in SCOPe 2.04: d2wo3b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2wo3A (A:)
    etgevtlldsrsvqgelgwiaspleggweevsimdekntpirtyqvcnvmepsqnnwlrt
    dwitregaqrvyieikftlrdcnslpgvmgtcketfnlyyyesdndkerfirenqfvkid
    tiaadesftqvdigdrimklnteirdvgplskkgfylafqdvgacialvsvrvfykrtkh
    hhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wo3A (A:)
    tgevtlldsrsvqgelgwiaspleggweevsimdekntpirtyqvcnvmepsqnnwlrtd
    witregaqrvyieikftlrdcnslpgvmgtcketfnlyyyesdndkerfirenqfvkidt
    iaadesftqvdigdrimklnteirdvgplskkgfylafqdvgacialvsvrvfykr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2wo3B (B:)
    etgnsdryavywnrsnprfhagagddgggytvevsindyldiycphygaplppaermehy
    vlymvngeghascdhrqrgfkrwecnrpaapggplkfsekfqlftpfslgfefrpgheyy
    yisatppnavdrpclrlkvyvrptqetlgtkhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wo3B (B:)
    nsdryavywnrsnprfhagagddgggytvevsindyldiycphygaplppaermehyvly
    mvngeghascdhrqrgfkrwecnrpaapggplkfsekfqlftpfslgfefrpgheyyyis
    atppnavdrpclrlkvyvrptq