PDB entry 2wo2

View 2wo2 on RCSB PDB site
Description: Crystal Structure of the EphA4-ephrinB2 complex
Class: transferase/signaling protein
Keywords: transferase-signaling protein complex, osteogenesis, axon guidance, cell surface receptor, developmental protein, neurogenesis, cell signaling
Deposited on 2009-07-21, released 2009-10-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ephrin type-a receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54764 (3-175)
      • expression tag (1-2)
      • expression tag (176-178)
    Domains in SCOPe 2.08: d2wo2a1, d2wo2a2, d2wo2a3
  • Chain 'B':
    Compound: ephrin-b2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wo2b_
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wo2A (A:)
etgevtlldsrsvqgelgwiaspleggweevsimdekntpirtyqvcnvmepsqnnwlrt
dwitregaqrvyieikftlrdcnslpgvmgtcketfnlyyyesdndkerfirenqfvkid
tiaadesftqvdigdrimklnteirdvgplskkgfylafqdvgacialvsvrvfykrtkh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2wo2A (A:)
tgevtlldsrsvqgelgwiaspleggweevsimdekntpirtyqvcnvmepsqnnwlrtd
witregaqrvyieikftlrdcnslpgvmgtcketfnlyyyesdndkerfirenqfvkidt
iaadesftqvdigdrimklnteirdvgplskkgfylafqdvgacialvsvrvfykrtk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wo2B (B:)
etgsivlepiywnssnskflpgqglvlypqigdkldiicpkvdsktvgqyeyykvymvdk
dqadrctikkentpllncakpdqdikftikfqefspnlwglefqknkdyyiistsngsle
gldnqeggvcqtramkilmkvgqdgtkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2wo2B (B:)
ivlepiywnssnskflpgqglvlypqigdkldiicpkvdgqyeyykvymvdkdqadrcti
kkentpllncakpdqdikftikfqefspnlwglefqknkdyyiistsngslegldnqegg
vcqtramkilmkvgqd