PDB entry 2wmt
View 2wmt on RCSB PDB site
Description: crystal structure of checkpoint kinase 1 (chk1) in complex with inhibitors
Class: transferase
Keywords: serine/threonine-protein kinase, phosphoprotein, isopeptide bond, checkpoint kinase, nucleotide-binding, serine/threonine kinase, DNA damage, DNA repair, ATP-binding, transferase, chk1, kinase, nucleus, cell cycle
Deposited on
2009-07-03, released
2009-07-28
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-10-12, with a file datestamp of
2011-10-07.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.2162
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Serine/threonine-protein kinase Chk1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d2wmta_ - Heterogens: ZYT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2wmtA (A:)
mavpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicink
mlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvy
lhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellk
rrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsapla
llhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsespsg
Sequence, based on observed residues (ATOM records): (download)
>2wmtA (A:)
dwdlvqtlgevqlavnrvteeavavkivdmnikkeicinkmlnhenvvkfyghrreiqyl
fleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpenlllderd
nlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscgivltaml
agelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsaritipdikkd
rwynkplk