PDB entry 2wl4

View 2wl4 on RCSB PDB site
Description: biosynthetic thiolase from z. ramigera. complex of the h348a mutant with coenzyme a.
Class: transferase
Keywords: acyltransferase, phb biosynthesis, thiolase fold, transferase
Deposited on 2009-06-22, released 2009-11-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-11-02, with a file datestamp of 2011-10-28.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.2327
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • see remark 999 (128)
      • engineered mutation (347)
    • PDB 2WL4 (10-10)
    Domains in SCOPe 2.03: d2wl4a1, d2wl4a2
  • Chain 'B':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • see remark 999 (128)
      • engineered mutation (347)
    • PDB 2WL4 (10-10)
    Domains in SCOPe 2.03: d2wl4b1, d2wl4b2
  • Chain 'C':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • see remark 999 (128)
      • engineered mutation (347)
    • PDB 2WL4 (10-10)
    Domains in SCOPe 2.03: d2wl4c1, d2wl4c2
  • Chain 'D':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • see remark 999 (128)
      • engineered mutation (347)
    • PDB 2WL4 (10-10)
  • Heterogens: SO4, COA, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wl4A (A:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaigapigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wl4A (A:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaigapigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wl4B (B:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaigapigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wl4B (B:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaigapigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2wl4C (C:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaigapigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wl4C (C:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaigapigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'D':
    No sequence available.