PDB entry 2wkh

View 2wkh on RCSB PDB site
Description: Crystal structure of the acyl-enzyme OXA-10 K70C-Ampicillin at pH 7
Class: hydrolase
Keywords: hydrolase, antibiotic resistance, class d beta-lactamase, plasmid encoded
Deposited on 2009-06-11, released 2010-08-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-10-01, with a file datestamp of 2014-09-26.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: 0.2032
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase oxa-10
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14489
      • engineered mutation (51)
    Domains in SCOPe 2.08: d2wkha_
  • Chain 'B':
    Compound: beta-lactamase oxa-10
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14489 (1-End)
      • expression tag (0)
      • engineered mutation (51)
    Domains in SCOPe 2.08: d2wkhb1, d2wkhb2
  • Heterogens: ZZ7, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wkhA (A:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfcipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfwlegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegiigg

    Sequence, based on observed residues (ATOM records): (download) 
    >2wkhA (A:)
sitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfcipnaiiglet
gviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkkfs
ygnqnisggidkfwlegqlrisavnqvefleslylnklsaskenqlivkealvteaapey
lvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkimes
egii

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wkhB (B:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfcipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfwlegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegiigg

    Sequence, based on observed residues (ATOM records): (download) 
    >2wkhB (B:)
mgsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfcipnaiigl
etgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkk
fsygnqnisggidkfwlegqlrisavnqvefleslylnklsaskenqlivkealvteaap
eylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkim
esegii