PDB entry 2wj4

View 2wj4 on RCSB PDB site
Description: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter nitroguajacolicus ru61a anaerobically complexed with its natural substrate 1-h-3-hydroxy-4-oxoquinaldine
Deposited on 2009-05-20, released 2010-01-26
The last revision was dated 2010-01-26, with a file datestamp of 2010-01-22.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.17746
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase
    Species: ARTHROBACTER NITROGUAJACOLICUS [TaxId:211146]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4V8M9
      • engineered mutation (68)
  • Chain 'B':
    Compound: 1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase
    Species: ARTHROBACTER NITROGUAJACOLICUS [TaxId:211146]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4V8M9
      • engineered mutation (68)
  • Chain 'C':
    Compound: 1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase
    Species: ARTHROBACTER NITROGUAJACOLICUS [TaxId:211146]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4V8M9
      • engineered mutation (68)
  • Chain 'D':
    Compound: 1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase
    Species: ARTHROBACTER NITROGUAJACOLICUS [TaxId:211146]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4V8M9
      • engineered mutation (68)
  • Heterogens: GOL, K, HQD, SRT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2wj4A (A:)
mtdtylhetlvfdnklsyidnqrdtdgpailllpgwchdhrvykyliqeldadfrvivpn
wrghglspsevpdfgyqeqvkdaleildqlgvetflpvshshggwvlvelleqagperap
rgiimdwlmwapkpdfaksltllkdperwregthglfdvwldghdekrvrhhlleemady
gydcwgrsgrviedaygrngspmqmmanltktrpirhifsqptepeyekinsdfaeqhpw
fsyaklggpthfpaidvpdraavhirefatairqgq

    Sequence, based on observed residues (ATOM records):
    >2wj4A (A:)
tdtylhetlvfdnklsyidnqrdtdgpailllpgwchdhrvykyliqeldadfrvivpnw
rghglspsevpdfgyqeqvkdaleildqlgvetflpvshshggwvlvelleqagperapr
giimdwlmwapkpdfaksltllkdperwregthglfdvwldghdekrvrhhlleemadyg
ydcwgrsgrviedaygrngspmqmmanltktrpirhifsqptepeyekinsdfaeqhpwf
syaklggpthfpaidvpdraavhirefatairqg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wj4B (B:)
mtdtylhetlvfdnklsyidnqrdtdgpailllpgwchdhrvykyliqeldadfrvivpn
wrghglspsevpdfgyqeqvkdaleildqlgvetflpvshshggwvlvelleqagperap
rgiimdwlmwapkpdfaksltllkdperwregthglfdvwldghdekrvrhhlleemady
gydcwgrsgrviedaygrngspmqmmanltktrpirhifsqptepeyekinsdfaeqhpw
fsyaklggpthfpaidvpdraavhirefatairqgq

    Sequence, based on observed residues (ATOM records):
    >2wj4B (B:)
dtylhetlvfdnklsyidnqrdtdgpailllpgwchdhrvykyliqeldadfrvivpnwr
ghglspsevpdfgyqeqvkdaleildqlgvetflpvshshggwvlvelleqagperaprg
iimdwlmwapkpdfaksltllkdperwregthglfdvwldghdekrvrhhlleemadygy
dcwgrsgrviedaygrngspmqmmanltktrpirhifsqptepeyekinsdfaeqhpwfs
yaklggpthfpaidvpdraavhirefatairqg

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2wj4C (C:)
mtdtylhetlvfdnklsyidnqrdtdgpailllpgwchdhrvykyliqeldadfrvivpn
wrghglspsevpdfgyqeqvkdaleildqlgvetflpvshshggwvlvelleqagperap
rgiimdwlmwapkpdfaksltllkdperwregthglfdvwldghdekrvrhhlleemady
gydcwgrsgrviedaygrngspmqmmanltktrpirhifsqptepeyekinsdfaeqhpw
fsyaklggpthfpaidvpdraavhirefatairqgq

    Sequence, based on observed residues (ATOM records):
    >2wj4C (C:)
tdtylhetlvfdnklsyidnqrdtdgpailllpgwchdhrvykyliqeldadfrvivpnw
rghglspsevpdfgyqeqvkdaleildqlgvetflpvshshggwvlvelleqagperapr
giimdwlmwapkpdfaksltllkdperwregthglfdvwldghdekrvrhhlleemadyg
ydcwgrsgrviedaygrngspmqmmanltktrpirhifsqptepeyekinsdfaeqhpwf
syaklggpthfpaidvpdraavhirefatairq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2wj4D (D:)
mtdtylhetlvfdnklsyidnqrdtdgpailllpgwchdhrvykyliqeldadfrvivpn
wrghglspsevpdfgyqeqvkdaleildqlgvetflpvshshggwvlvelleqagperap
rgiimdwlmwapkpdfaksltllkdperwregthglfdvwldghdekrvrhhlleemady
gydcwgrsgrviedaygrngspmqmmanltktrpirhifsqptepeyekinsdfaeqhpw
fsyaklggpthfpaidvpdraavhirefatairqgq

    Sequence, based on observed residues (ATOM records):
    >2wj4D (D:)
tdtylhetlvfdnklsyidnqrdtdgpailllpgwchdhrvykyliqeldadfrvivpnw
rghglspsevpdfgyqeqvkdaleildqlgvetflpvshshggwvlvelleqagperapr
giimdwlmwapkpdfaksltllkdperwregthglfdvwldghdekrvrhhlleemadyg
ydcwgrsgrviedaygrngspmqmmanltktrpirhifsqptepeyekinsdfaeqhpwf
syaklggpthfpaidvpdraavhirefatairq