PDB entry 2wh0

View 2wh0 on RCSB PDB site
Description: recognition of an intrachain tandem 14-3-3 binding site within protein kinase c epsilon
Deposited on 2009-04-28, released 2009-08-18
The last revision was dated 2009-10-27, with a file datestamp of 2009-10-23.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.183
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14-3-3 protein zeta/delta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: 14-3-3 protein zeta/delta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: 14-3-3 protein zeta/delta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: 14-3-3 protein zeta/delta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: protein kinase c epsilon type, npkc-epsilon
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: protein kinase c epsilon type, npkc-epsilon
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PGE, CA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2wh0A (A:)
mdknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsswr
vvssieqktegaekkqqmareyrekietelrdicndvlsllekflipnasqaeskvfylk
mkgdyyrylaevaagddkkgivdqsqqayqeafeiskkemqpthpirlglalnfsvfyye
ilnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwtsdtqgdeaeag
eggen

    Sequence, based on observed residues (ATOM records):
    >2wh0A (A:)
dknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsswrv
vssieqkteaekkqqmareyrekietelrdicndvlsllekflipnasqaeskvfylkmk
gdyyrylaevaagddkkgivdqsqqayqeafeiskkemqpthpirlglalnfsvfyyeil
nspekacslaktafdeaiaelsykdstlimqllrdnltlwt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wh0B (B:)
mdknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsswr
vvssieqktegaekkqqmareyrekietelrdicndvlsllekflipnasqaeskvfylk
mkgdyyrylaevaagddkkgivdqsqqayqeafeiskkemqpthpirlglalnfsvfyye
ilnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwtsdtqgdeaeag
eggen

    Sequence, based on observed residues (ATOM records):
    >2wh0B (B:)
dknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsswrv
vssieqktegaekkqqmareyrekietelrdicndvlsllekflipnasqaeskvfylkm
kgdyyrylaevaagddkkgivdqsqqayqeafeiskkemqpthpirlglalnfsvfyyei
lnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlw

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2wh0C (C:)
mdknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsswr
vvssieqktegaekkqqmareyrekietelrdicndvlsllekflipnasqaeskvfylk
mkgdyyrylaevaagddkkgivdqsqqayqeafeiskkemqpthpirlglalnfsvfyye
ilnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwtsdtqgdeaeag
eggen

    Sequence, based on observed residues (ATOM records):
    >2wh0C (C:)
nelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsswrvvs
sieqktegaekkqqmareyrekietelrdicndvlsllekflipnasqaeskvfylkmkg
dyyrylaevaagddkkgivdqsqqayqeafeiskkemqpthpirlglalnfsvfyyeiln
spekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwt

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2wh0D (D:)
mdknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsswr
vvssieqktegaekkqqmareyrekietelrdicndvlsllekflipnasqaeskvfylk
mkgdyyrylaevaagddkkgivdqsqqayqeafeiskkemqpthpirlglalnfsvfyye
ilnspekacslaktafdeaiaeldtlseesykdstlimqllrdnltlwtsdtqgdeaeag
eggen

    Sequence, based on observed residues (ATOM records):
    >2wh0D (D:)
dknelvqkaklaeqaeryddmaacmksvteqgaelsneernllsvayknvvgarrsswrv
vssieaekkqqmareyrekietelrdicndvlsllekflipnasqaeskvfylkmkgdyy
rylaevaagddkkgivdqsqqayqeafeiskkemqpthpirlglalnfsvfyyeilnspe
kacslaktafdeaiaeldlseesykdstlimqllrdnltlwt

  • Chain 'Q':
    Sequence, based on SEQRES records:
    >2wh0Q (Q:)
drsksaptspcdqeikelennirkalsfdnr

    Sequence, based on observed residues (ATOM records):
    >2wh0Q (Q:)
rsksakalsfdnr

  • Chain 'R':
    Sequence, based on SEQRES records:
    >2wh0R (R:)
drsksaptspcdqeikelennirkalsfdnr

    Sequence, based on observed residues (ATOM records):
    >2wh0R (R:)
rsksaalsf