PDB entry 2weu

View 2weu on RCSB PDB site
Description: crystal structure of tryptophan 5-halogenase (pyrh) complex with substrate tryptophan
Deposited on 2009-04-01, released 2009-04-14
The last revision was dated 2011-07-13, with a file datestamp of 2011-06-02.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.216
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tryptophan 5-halogenase
    Species: STREPTOMYCES RUGOSPORUS [TaxId:295838]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: tryptophan 5-halogenase
    Species: STREPTOMYCES RUGOSPORUS [TaxId:295838]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: tryptophan 5-halogenase
    Species: STREPTOMYCES RUGOSPORUS [TaxId:295838]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: tryptophan 5-halogenase
    Species: STREPTOMYCES RUGOSPORUS [TaxId:295838]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: TRP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2weuA (A:)
mirsvvivgggtagwmtasylkaafddridvtlvesgnvrrigvgeatfstvrhffdylg
lderewlprcaggyklgirfenwsepgeyfyhpferlrvvdgfnmaewwlavgdrrtsfs
eacylthrlceakraprmldgslfasqvdeslgrstlaeqraqfpyayhfdadevaryls
eyaiargvrhvvddvqhvgqdergwisgvhtkqhgeisgdlfvdctgfrgllinqtlggr
fqsfsdvlpnnravalrvprendedmrpyttatamsagwmwtiplfkrdgngyvysdefi
speeaerelrstvapgrddleanhiqmrigrnertwinncvavglsaafveplestgiff
iqhaieqlvkhfpgerwdpvlisaynermahmvdgvkeflvlhykgaqredtpywkaakt
rampdglarklelsashlldeqtiypyyhgfetyswitmnlglgivperprpallhmdpa
palaeferlrregdeliaalpscyeylasiq

    Sequence, based on observed residues (ATOM records):
    >2weuA (A:)
mirsvvivgggtagwmtasylkaafddridvtlvesvgeatfstvrhffdylglderewl
prcaggyklgirfenwsepgeyfyhpferlrvvdgfnmaewwlavgsfseacylthrlce
akraprmldgslfalgrstlaeqraqfpyayhfdadevarylseyaiargvrhvvddvqh
vgqdergwisgvhtkqhgeisgdlfvdctgfrgllinqtlggrfqsfsdvlpnnravalr
vprendedmrpyttatamsagwmwtiplfkrdgngyvysdefispeeaerelrstvapgr
ddleanhiqmrigrnertwinncvavglsaafveplestgiffiqhaieqlvkhfpgerw
dpvlisaynermahmvdgvkeflvlhykgaqredtpywkaaktrampdglarklelsash
lldeqtiypyyhgfetyswitmnlglgivperprpallhmdpapalaeferlrregdeli
aalpscyeylasiq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2weuB (B:)
mirsvvivgggtagwmtasylkaafddridvtlvesgnvrrigvgeatfstvrhffdylg
lderewlprcaggyklgirfenwsepgeyfyhpferlrvvdgfnmaewwlavgdrrtsfs
eacylthrlceakraprmldgslfasqvdeslgrstlaeqraqfpyayhfdadevaryls
eyaiargvrhvvddvqhvgqdergwisgvhtkqhgeisgdlfvdctgfrgllinqtlggr
fqsfsdvlpnnravalrvprendedmrpyttatamsagwmwtiplfkrdgngyvysdefi
speeaerelrstvapgrddleanhiqmrigrnertwinncvavglsaafveplestgiff
iqhaieqlvkhfpgerwdpvlisaynermahmvdgvkeflvlhykgaqredtpywkaakt
rampdglarklelsashlldeqtiypyyhgfetyswitmnlglgivperprpallhmdpa
palaeferlrregdeliaalpscyeylasiq

    Sequence, based on observed residues (ATOM records):
    >2weuB (B:)
mirsvvivgggtagwmtasylkaafddridvtlvesgvgeatfstvrhffdylglderew
lprcaggyklgirfenwsepgeyfyhpferlrvvdgfnmaewwlavgdrrtsfseacylt
hrlceakraprmldgslfslgrstlaeqraqfpyayhfdadevarylseyaiargvrhvv
ddvqhvgqdergwisgvhtkqhgeisgdlfvdctgfrgllinqtlggrfqsfsdvlpnnr
avalrvprendedmrpyttatamsagwmwtiplfkrdgngyvysdefispeeaerelrst
vapgrddleanhiqmrigrnertwinncvavglsaafveplestgiffiqhaieqlvkhf
pgerwdpvlisaynermahmvdgvkeflvlhykgaqredtpywkaaktrampdglarkle
lsashlldeqtiypyyhgfetyswitmnlglgivperprpallhmdpapalaeferlrre
gdeliaalpscyeylasiq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2weuC (C:)
mirsvvivgggtagwmtasylkaafddridvtlvesgnvrrigvgeatfstvrhffdylg
lderewlprcaggyklgirfenwsepgeyfyhpferlrvvdgfnmaewwlavgdrrtsfs
eacylthrlceakraprmldgslfasqvdeslgrstlaeqraqfpyayhfdadevaryls
eyaiargvrhvvddvqhvgqdergwisgvhtkqhgeisgdlfvdctgfrgllinqtlggr
fqsfsdvlpnnravalrvprendedmrpyttatamsagwmwtiplfkrdgngyvysdefi
speeaerelrstvapgrddleanhiqmrigrnertwinncvavglsaafveplestgiff
iqhaieqlvkhfpgerwdpvlisaynermahmvdgvkeflvlhykgaqredtpywkaakt
rampdglarklelsashlldeqtiypyyhgfetyswitmnlglgivperprpallhmdpa
palaeferlrregdeliaalpscyeylasiq

    Sequence, based on observed residues (ATOM records):
    >2weuC (C:)
mirsvvivgggtagwmtasylkaafddridvtlvesgnvvgeatfstvrhffdylglder
ewlprcaggyklgirfenwsepgeyfyhpferlrvvdgfnmaewwlavgdrtsfseacyl
thrlceakraprmldgslfagrstlaeqraqfpyayhfdadevarylseyaiargvrhvv
ddvqhvgqdergwisgvhtkqhgeisgdlfvdctgfrgllinqtlggrfqsfsdvlpnnr
avalrvprendedmrpyttatamsagwmwtiplfkrdgngyvysdefispeeaerelrst
vapgrddleanhiqmrigrnertwinncvavglsaafveplestgiffiqhaieqlvkhf
pgerwdpvlisaynermahmvdgvkeflvlhykgaqredtpywkaaktrampdglarkle
lsashlldeqtiypyyhgfetyswitmnlglgivperprpallhmdpapalaeferlrre
gdeliaalpscyeylasiq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2weuD (D:)
mirsvvivgggtagwmtasylkaafddridvtlvesgnvrrigvgeatfstvrhffdylg
lderewlprcaggyklgirfenwsepgeyfyhpferlrvvdgfnmaewwlavgdrrtsfs
eacylthrlceakraprmldgslfasqvdeslgrstlaeqraqfpyayhfdadevaryls
eyaiargvrhvvddvqhvgqdergwisgvhtkqhgeisgdlfvdctgfrgllinqtlggr
fqsfsdvlpnnravalrvprendedmrpyttatamsagwmwtiplfkrdgngyvysdefi
speeaerelrstvapgrddleanhiqmrigrnertwinncvavglsaafveplestgiff
iqhaieqlvkhfpgerwdpvlisaynermahmvdgvkeflvlhykgaqredtpywkaakt
rampdglarklelsashlldeqtiypyyhgfetyswitmnlglgivperprpallhmdpa
palaeferlrregdeliaalpscyeylasiq

    Sequence, based on observed residues (ATOM records):
    >2weuD (D:)
mirsvvivgggtagwmtasylkaafddridvtlvesgvgeatfstvrhffdylglderew
lprcaggyklgirfenwsepgeyfyhpferlrvvdgfnmaewwlavgdtsfseacylthr
lceakraprmldgslfaslgrstlaeqraqfpyayhfdadevarylseyaiargvrhvvd
dvqhvgqdergwisgvhtkqhgeisgdlfvdctgfrgllinqtlggrfqsfsdvlpnnra
valrvprendedmrpyttatamsagwmwtiplfkrdgngyvysdefispeeaerelrstv
apgrddleanhiqmrigrnertwinncvavglsaafveplestgiffiqhaieqlvkhfp
gerwdpvlisaynermahmvdgvkeflvlhykgaqredtpywkaaktrampdglarklel
sashlldeqtiypyyhgfetyswitmnlglgivperprpallhmdpapalaeferlrreg
deliaalpscyeylasiq