PDB entry 2wek

View 2wek on RCSB PDB site
Description: crystal structure of the human mgc45594 gene product in complex with diclofenac
Deposited on 2009-03-31, released 2009-12-15
The last revision was dated 2011-07-13, with a file datestamp of 2011-06-02.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.168
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: zinc-binding alcohol dehydrogenase domain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WEK (0-1)
    • Uniprot Q8N4Q0 (2-340)
  • Chain 'B':
    Compound: zinc-binding alcohol dehydrogenase domain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WEK (Start-1)
    • Uniprot Q8N4Q0 (2-340)
  • Heterogens: NAP, DIF, PO4, CL, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >2wekA (A:)
smmqklvvtrlspnfreavtlsrdcpvplpgdgdllvrnrfvgvnasdinysagrydpsv
kppfdigfegigevvalglsasarytvgqavaymapgsfaeytvvpasiatpvpsvkpey
ltllvsgttayislkelgglsegkkvlvtaaaggtgqfamqlskkakchvigtcssdeks
aflkslgcdrpinyktepvgtvlkqeypegvdvvyesvggamfdlavdalatkgrlivig
fisgyqtptglspvkagtlpakllkksasvqgfflnhylskyqaamshllemcvsgdlvc
evdlgdlspegrftglesifravnymymgkntgkivvelph

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wekB (B:)
smmqklvvtrlspnfreavtlsrdcpvplpgdgdllvrnrfvgvnasdinysagrydpsv
kppfdigfegigevvalglsasarytvgqavaymapgsfaeytvvpasiatpvpsvkpey
ltllvsgttayislkelgglsegkkvlvtaaaggtgqfamqlskkakchvigtcssdeks
aflkslgcdrpinyktepvgtvlkqeypegvdvvyesvggamfdlavdalatkgrlivig
fisgyqtptglspvkagtlpakllkksasvqgfflnhylskyqaamshllemcvsgdlvc
evdlgdlspegrftglesifravnymymgkntgkivvelph

    Sequence, based on observed residues (ATOM records):
    >2wekB (B:)
mmqklvvtrlspnfreavtlsrdcpvplpgdgdllvrnrfvgvnasdinysagrydpsvk
ppfdigfegigevvalglsasarytvgqavaymapgsfaeytvvpasiatpvpsvkpeyl
tllvsgttayislkelgglsegkkvlvtaaaggtgqfamqlskkakchvigtcssdeksa
flkslgcdrpinyktepvgtvlkqeypegvdvvyesvggamfdlavdalatkgrlivigf
isgyqtptglspvkagtlpakllkksasvqgfflnhylskyqaamshllemcvsgdlvce
vdlgdlspegrftglesifravnymymgkntgkivvelph