PDB entry 2we1

View 2we1 on RCSB PDB site
Description: ebv dutpase mutant asp131asn with bound dump
Class: hydrolase
Keywords: pyrophosphatase, epstein-barr virus, nucleotide metabolism, dutpase, monomer, hydrolase, herpes virus
Deposited on 2009-03-27, released 2009-07-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-09-15, with a file datestamp of 2009-09-11.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.1982
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxyuridine 5'-triphosphate nucleotidohydrolase
    Species: HUMAN HERPESVIRUS 4 [TaxId:10377]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WE1
      • engineered mutation (138)
    • Uniprot P03195
    Domains in SCOPe 2.08: d2we1a1, d2we1a2
  • Heterogens: UMP, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2we1A (A:)
gamgsgipmeacphiryafqndklllqqasvgrltlvnkttillrpmktttvdlglyarp
peghglmlwgstsrpvtshvgiidpgytgelrlilqnqrrynstlrpselkihlaafrya
tpqmeedkgpinhpqypgnvgldvslpkdlalfphqtvsvtltvpppsiphhrptifgrs
glamqgilvkpcrwrrggvdvsltnfsdqtvflnkyrrfcqlvylhkhhltsfysphsda
gvlgprslfrwasctfeevpslamgdsglsealegrqgrgfgssgq

    Sequence, based on observed residues (ATOM records): (download) 
    >2we1A (A:)
cphiryafqndklllqqasvgrltlvnkttillrpmktttvdlglyarppeghglmlwgs
tsrpvtshvgiidpgytgelrlilqnqrrynstlrpselkihlaafryatpqmgpinpgn
vgldvslpkdlalfphqtvsvtltvpppsiphhrptifgrsglamqgilvkpcrwrrggv
dvsltnfsdqtvflnkyrrfcqlvylhkhhltsfysphsdagvlgprslfrwasctfeev
pslam