PDB entry 2wdt

View 2wdt on RCSB PDB site
Description: crystal structure of plasmodium falciparum uchl3 in complex with the suicide inhibitor ubvme
Class: hydrolase/protein binding
Keywords: hydrolase-protein binding complex, enzyme-ligand complex, ubiquitin isopeptidase, uch-l superfamily, cystein proteinase, peptidase_c12, hydrolase
Deposited on 2009-03-26, released 2009-12-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-06-02.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.188
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ubiquitin carboxyl-terminal hydrolase l3
    Species: PLASMODIUM FALCIPARUM [TaxId:5833]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WDT
    Domains in SCOPe 2.07: d2wdta_
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62988 (0-74)
    • PDB 2WDT (75-75)
    Domains in SCOPe 2.07: d2wdtb1, d2wdtb2
  • Chain 'C':
    Compound: ubiquitin carboxyl-terminal hydrolase l3
    Species: PLASMODIUM FALCIPARUM [TaxId:5833]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WDT
    Domains in SCOPe 2.07: d2wdtc_
  • Chain 'D':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62988 (0-74)
    • PDB 2WDT (75-75)
    Domains in SCOPe 2.07: d2wdtd1, d2wdtd2
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2wdtA (A:)
    makndiwtplesnpdslylyscklgqsklkfvdiygfnndlldmipqpvqaviflypvnd
    nivsenntndkhnlkenfdnvwfikqyipnscgtiallhlygnlrnkfeldkdsvlddff
    nkvnemsaekrgqelknnksienlhhefcgqvenrddildvdthfivfvqiegkiieldg
    rkdhptvhcftngdnflydtgkiiqdkfiekckddlrfsalavipndnfdii
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wdtA (A:)
    diwtplesnpdslylyscklgqsklkfvdiygfnndlldmipqpvqaviflypvnfdnvw
    fikqyipnscgtiallhlygnlrnkfeldkdsvlddffnkvnemsaekrgqelknnksie
    nlhhefcgqvenrddildvdthfivfvqiegkiieldgrkdhptvhcftngdnflydtgk
    iiqdkfiekckddlrfsalavipn
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2wdtB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgx
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2wdtC (C:)
    makndiwtplesnpdslylyscklgqsklkfvdiygfnndlldmipqpvqaviflypvnd
    nivsenntndkhnlkenfdnvwfikqyipnscgtiallhlygnlrnkfeldkdsvlddff
    nkvnemsaekrgqelknnksienlhhefcgqvenrddildvdthfivfvqiegkiieldg
    rkdhptvhcftngdnflydtgkiiqdkfiekckddlrfsalavipndnfdii
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wdtC (C:)
    ndiwtplesnpdslylyscklgqsklkfvdiygfnndlldmipqpvqaviflypvnfdnv
    wfikqyipnscgtiallhlygnlrnkfeldkdsvlddffnkvnemsaekrgqelknnksi
    enlhhefcgqvenrddildvdthfivfvqiegkiieldgrkdhptvhcftngdnflydtg
    kiiqdkfiekckddlrfsalavipnd
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2wdtD (D:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgx