PDB entry 2wc3

View 2wc3 on RCSB PDB site
Description: Structure of family 1 beta-glucosidase from Thermotoga maritima in complex with 3-imino-2-oxa-(+)-8-epi-castanospermine
Class: hydrolase
Keywords: castanospermine, glycoside hydrolase, polysaccharide degradation, cellulose degradation, carbohydrate metabolism, family 1, hydrolase, inhibitors, glycosidase
Deposited on 2009-03-08, released 2009-04-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-07-12, with a file datestamp of 2017-07-07.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-glucosidase a
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WC3
    • Uniprot Q08638 (23-End)
    Domains in SCOPe 2.07: d2wc3a_
  • Chain 'B':
    Compound: beta-glucosidase a
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WC3
    • Uniprot Q08638 (23-End)
    Domains in SCOPe 2.07: d2wc3b_
  • Chain 'C':
    Compound: beta-glucosidase a
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wc3c_
  • Chain 'D':
    Compound: beta-glucosidase a
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wc3d_
  • Heterogens: AM3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wc3A (A:)
mgsshhhhhhssglvprgshmasnvkkfpegflwgvatasyqiegspladgagmsiwhtf
shtpgnvkngdtgdvacdhynrwkedieiieklgvkayrfsiswprilpegtgrvnqkgl
dfynriidtllekgitpfvtiyhwdlpfalqlkggwanreiadwfaeysrvlfenfgdrv
knwitlnepwvvaivghlygvhapgmrdiyvafravhnllraharavkvfretvkdgkig
ivfnngyfepasekeediravrfmhqfnnyplflnpiyrgdypelvlefareylpenykd
dmseiqekidfvglnyysghlvkfdpdapakvsfverdlpktamgweivpegiywilkkv
keeynppevyitengaafddvvsedgrvhdqnridylkahigqawkaiqegvplkgyfvw
slldnfewaegyskrfgivyvdystqkrivkdsgywysnvvknngled

    Sequence, based on observed residues (ATOM records): (download) 
    >2wc3A (A:)
nvkkfpegflwgvatasyqiegspladgagmsiwhtfshtpgnvkngdtgdvacdhynrw
kedieiieklgvkayrfsiswprilpegtgrvnqkgldfynriidtllekgitpfvtiyh
wdlpfalqlkggwanreiadwfaeysrvlfenfgdrvknwitlnepwvvaivghlygvha
pgmrdiyvafravhnllraharavkvfretvkdgkigivfnngyfepasekeediravrf
mhqfnnyplflnpiyrgdypelvlefareylpenykddmseiqekidfvglnyysghlvk
fdpdakvsfverdlpktamgweivpegiywilkkvkeeynppevyitengaafddvvsed
grvhdqnridylkahigqawkaiqegvplkgyfvwslldnfewaegyskrfgivyvdyst
qkrivkdsgywysnvvknngle

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wc3B (B:)
mgsshhhhhhssglvprgshmasnvkkfpegflwgvatasyqiegspladgagmsiwhtf
shtpgnvkngdtgdvacdhynrwkedieiieklgvkayrfsiswprilpegtgrvnqkgl
dfynriidtllekgitpfvtiyhwdlpfalqlkggwanreiadwfaeysrvlfenfgdrv
knwitlnepwvvaivghlygvhapgmrdiyvafravhnllraharavkvfretvkdgkig
ivfnngyfepasekeediravrfmhqfnnyplflnpiyrgdypelvlefareylpenykd
dmseiqekidfvglnyysghlvkfdpdapakvsfverdlpktamgweivpegiywilkkv
keeynppevyitengaafddvvsedgrvhdqnridylkahigqawkaiqegvplkgyfvw
slldnfewaegyskrfgivyvdystqkrivkdsgywysnvvknngled

    Sequence, based on observed residues (ATOM records): (download) 
    >2wc3B (B:)
nvkkfpegflwgvatasyqiegspladgagmsiwhtfshtpgnvkngdtgdvacdhynrw
kedieiieklgvkayrfsiswprilpegtgrvnqkgldfynriidtllekgitpfvtiyh
wdlpfalqlkggwanreiadwfaeysrvlfenfgdrvknwitlnepwvvaivghlygvha
pgmrdiyvafravhnllraharavkvfretvkdgkigivfnngyfepasekeediravrf
mhqfnnyplflnpiyrgdypelvlefareylpenykddmseiqekidfvglnyysghlvk
fdpdapakvsfverdlpktamgweivpegiywilkkvkeeynppevyitengaafddvvs
edgrvhdqnridylkahigqawkaiqegvplkgyfvwslldnfewaegyskrfgivyvdy
stqkrivkdsgywysnvvknngle

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2wc3C (C:)
mgsshhhhhhssglvprgshmasnvkkfpegflwgvatasyqiegspladgagmsiwhtf
shtpgnvkngdtgdvacdhynrwkedieiieklgvkayrfsiswprilpegtgrvnqkgl
dfynriidtllekgitpfvtiyhwdlpfalqlkggwanreiadwfaeysrvlfenfgdrv
knwitlnepwvvaivghlygvhapgmrdiyvafravhnllraharavkvfretvkdgkig
ivfnngyfepasekeediravrfmhqfnnyplflnpiyrgdypelvlefareylpenykd
dmseiqekidfvglnyysghlvkfdpdapakvsfverdlpktamgweivpegiywilkkv
keeynppevyitengaafddvvsedgrvhdqnridylkahigqawkaiqegvplkgyfvw
slldnfewaegyskrfgivyvdystqkrivkdsgywysnvvknngled

    Sequence, based on observed residues (ATOM records): (download) 
    >2wc3C (C:)
vkkfpegflwgvatasyqiegspladgagmsiwhtfshtpgnvkngdtgdvacdhynrwk
edieiieklgvkayrfsiswprilpegtgrvnqkgldfynriidtllekgitpfvtiyhw
dlpfalqlkggwanreiadwfaeysrvlfenfgdrvknwitlnepwvvaivghlygvhap
gmrdiyvafravhnllraharavkvfretvkdgkigivfnngyfepasekeediravrfm
hqfnnyplflnpiyrgdypelvlefareylpenykddmseiqekidfvglnyysghlvkf
dpdapakvsfverdlpktamgweivpegiywilkkvkeeynppevyitengaafddvvse
dgrvhdqnridylkahigqawkaiqegvplkgyfvwslldnfewaegyskrfgivyvdys
tqkrivkdsgywysnvvknngle

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2wc3D (D:)
mgsshhhhhhssglvprgshmasnvkkfpegflwgvatasyqiegspladgagmsiwhtf
shtpgnvkngdtgdvacdhynrwkedieiieklgvkayrfsiswprilpegtgrvnqkgl
dfynriidtllekgitpfvtiyhwdlpfalqlkggwanreiadwfaeysrvlfenfgdrv
knwitlnepwvvaivghlygvhapgmrdiyvafravhnllraharavkvfretvkdgkig
ivfnngyfepasekeediravrfmhqfnnyplflnpiyrgdypelvlefareylpenykd
dmseiqekidfvglnyysghlvkfdpdapakvsfverdlpktamgweivpegiywilkkv
keeynppevyitengaafddvvsedgrvhdqnridylkahigqawkaiqegvplkgyfvw
slldnfewaegyskrfgivyvdystqkrivkdsgywysnvvknngled

    Sequence, based on observed residues (ATOM records): (download) 
    >2wc3D (D:)
vkkfpegflwgvatasyqiegspladgagmsiwhtfshtpgnvkngdtgdvacdhynrwk
edieiieklgvkayrfsiswprilpegtgrvnqkgldfynriidtllekgitpfvtiyhw
dlpfalqlkggwanreiadwfaeysrvlfenfgdrvknwitlnepwvvaivghlygvhap
gmrdiyvafravhnllraharavkvfretvkdgkigivfnngyfepasekeediravrfm
hqfnnyplflnpiyrgdypelvlefareylpenykddmseiqekidfvglnyysghlvkf
dpdakvsfverdlpktamgweivpegiywilkkvkeeynppevyitengaafddvvsedg
rvhdqnridylkahigqawkaiqegvplkgyfvwslldnfewaegyskrfgivyvdystq
krivkdsgywysnvvknngle