PDB entry 2wad

View 2wad on RCSB PDB site
Description: penicillin-binding protein 2b (pbp-2b) from streptococcus pneumoniae (strain 5204)
Deposited on 2009-02-05, released 2009-02-24
The last revision was dated 2014-02-19, with a file datestamp of 2014-02-14.
Experiment type: XRAY
Resolution: 2.18 Å
R-factor: 0.213
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: penicillin-binding protein 2b
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:1313]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A3M6 (Start-679)
      • conflict see remark 9 (53)
      • conflict see remark 9 (55)
      • conflict see remark 9 (95)
      • conflict see remark 9 (129)
      • conflict see remark 9 (160)
      • conflict see remark 9 (224)
      • conflict see remark 9 (250)
      • conflict see remark 9 (274)
      • conflict see remark 9 (280)
      • conflict see remark 9 (289)
      • conflict see remark 9 (291)
      • conflict see remark 9 (296-297)
      • conflict see remark 9 (305)
      • conflict see remark 9 (332)
      • conflict see remark 9 (350)
      • conflict see remark 9 (360)
      • conflict see remark 9 (411)
      • conflict see remark 9 (421)
      • conflict see remark 9 (425-426)
      • conflict see remark 9 (437)
      • conflict see remark 9 (445)
      • conflict see remark 9 (447)
      • conflict see remark 9 (454)
      • conflict see remark 9 (475)
      • conflict see remark 9 (488)
      • conflict see remark 9 (501)
      • conflict see remark 9 (507)
      • conflict see remark 9 (511)
      • conflict see remark 9 (541)
      • conflict see remark 9 (544)
      • conflict see remark 9 (551)
      • conflict see remark 9 (560)
      • conflict see remark 9 (564-568)
      • conflict see remark 9 (570)
      • conflict see remark 9 (577)
      • conflict see remark 9 (581)
      • conflict see remark 9 (591)
      • conflict see remark 9 (596)
      • conflict see remark 9 (605)
      • conflict see remark 9 (608)
      • conflict see remark 9 (639-640)
      • conflict see remark 9 (658-659)
      • conflict see remark 9 (663)
      • conflict see remark 9 (673-675)
  • Chain 'B':
    Compound: penicillin-binding protein 2b
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:1313]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A3M6 (Start-679)
      • conflict see remark 9 (53)
      • conflict see remark 9 (55)
      • conflict see remark 9 (95)
      • conflict see remark 9 (129)
      • conflict see remark 9 (160)
      • conflict see remark 9 (224)
      • conflict see remark 9 (250)
      • conflict see remark 9 (274)
      • conflict see remark 9 (280)
      • conflict see remark 9 (289)
      • conflict see remark 9 (291)
      • conflict see remark 9 (296-297)
      • conflict see remark 9 (305)
      • conflict see remark 9 (332)
      • conflict see remark 9 (350)
      • conflict see remark 9 (360)
      • conflict see remark 9 (411)
      • conflict see remark 9 (421)
      • conflict see remark 9 (425-426)
      • conflict see remark 9 (437)
      • conflict see remark 9 (445)
      • conflict see remark 9 (447)
      • conflict see remark 9 (454)
      • conflict see remark 9 (475)
      • conflict see remark 9 (488)
      • conflict see remark 9 (501)
      • conflict see remark 9 (507)
      • conflict see remark 9 (511)
      • conflict see remark 9 (541)
      • conflict see remark 9 (544)
      • conflict see remark 9 (551)
      • conflict see remark 9 (560)
      • conflict see remark 9 (564-568)
      • conflict see remark 9 (570)
      • conflict see remark 9 (577)
      • conflict see remark 9 (581)
      • conflict see remark 9 (591)
      • conflict see remark 9 (596)
      • conflict see remark 9 (605)
      • conflict see remark 9 (608)
      • conflict see remark 9 (639-640)
      • conflict see remark 9 (658-659)
      • conflict see remark 9 (663)
      • conflict see remark 9 (673-675)
  • Chain 'C':
    Compound: penicillin-binding protein 2b
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:1313]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A3M6 (Start-679)
      • conflict see remark 9 (53)
      • conflict see remark 9 (55)
      • conflict see remark 9 (95)
      • conflict see remark 9 (129)
      • conflict see remark 9 (160)
      • conflict see remark 9 (224)
      • conflict see remark 9 (250)
      • conflict see remark 9 (274)
      • conflict see remark 9 (280)
      • conflict see remark 9 (289)
      • conflict see remark 9 (291)
      • conflict see remark 9 (296-297)
      • conflict see remark 9 (305)
      • conflict see remark 9 (332)
      • conflict see remark 9 (350)
      • conflict see remark 9 (360)
      • conflict see remark 9 (411)
      • conflict see remark 9 (421)
      • conflict see remark 9 (425-426)
      • conflict see remark 9 (437)
      • conflict see remark 9 (445)
      • conflict see remark 9 (447)
      • conflict see remark 9 (454)
      • conflict see remark 9 (475)
      • conflict see remark 9 (488)
      • conflict see remark 9 (501)
      • conflict see remark 9 (507)
      • conflict see remark 9 (511)
      • conflict see remark 9 (541)
      • conflict see remark 9 (544)
      • conflict see remark 9 (551)
      • conflict see remark 9 (560)
      • conflict see remark 9 (564-568)
      • conflict see remark 9 (570)
      • conflict see remark 9 (577)
      • conflict see remark 9 (581)
      • conflict see remark 9 (591)
      • conflict see remark 9 (596)
      • conflict see remark 9 (605)
      • conflict see remark 9 (608)
      • conflict see remark 9 (639-640)
      • conflict see remark 9 (658-659)
      • conflict see remark 9 (663)
      • conflict see remark 9 (673-675)
  • Heterogens: ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2wadA (A:)
mrkfnshsipirlnllfsivillfmtiigrllymqvlnkdfyekklasasqtkvttssar
geiydasgkplventlkqvvsftrsnkmtatdlkeiakklltyvsisspnlterqladyy
ladpeiykktvealpsekrldsdgnrlseselynnavdsvptsqlnytedekkeiylfsq
lnavgnfatgtiatdplndsqvaviasiskempgisistswdrkiletslssivgsvsse
kaglpaeeaesylkkgyslndrvgtsylekqyeevlqgkrpvkeihldkhgdmesvenie
egskgknikltidlafqdsvdallksyfnselgnggakysegvyavalnpqtgavlsmsg
lkhdlktgeltpdslgtvtnvfvpgsvvkaatissgwengvlsgnqtltdqpivfqgsap
iyswyklaygsfpitavealeyssnayvvqtalgimgqtyqpnmfvgtsnlesamgklrs
tfgeyglgsatgidlpdestglvpkeynfanfitnafgqfdnytpmqlaqyvatianngv
rlaphivegiydnndkgglgeliqaidtkeinkvnisesdmailhqgfyqvshgtspltt
grafsdgatvsisgktgtgesyvaggqeatntnavayaptenpqiavavvfphntnltkn
vgpaiardiinlynqhhpmn

    Sequence, based on observed residues (ATOM records):
    >2wadA (A:)
sqtkvttssargeiydasgkplventlkqvvsftrsnkmtatdlkeiakklltyvsissp
nlterqladyyladpeiykktvealpeselynnavdsvptsqlnytedekkeiylfsqln
avgnfatgtiatdplndsqvaviasiskempgisistswdrkiletslssivgsvsseka
glpaeeaesylkkgyslndrvgtsylekqyeevlqgkrpvkeihldkhgdmesvenieeg
skgknikltidlafqdsvdallksyfnselgnggakysegvyavalnpqtgavlsmsglk
hdlktgeltpdslgtvtnvfvpgsvvkaatissgwengvlsgnqtltdqpivfqgsapiy
swyklaygsfpitavealeyssnayvvqtalgimgqtyqpnmfvgtsnlesamgklrstf
geyglgsatgidlpdestglvpkeynfanfitnafgqfdnytpmqlaqyvatianngvrl
aphivegiydnndkgglgeliqaidtkeinkvnisesdmailhqgfyqvshgtsplttgr
afsdgatvsisgktgtntnavayaptenpqiavavvfphntnltknvgpaiardiinlyn
qhhpmn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2wadB (B:)
mrkfnshsipirlnllfsivillfmtiigrllymqvlnkdfyekklasasqtkvttssar
geiydasgkplventlkqvvsftrsnkmtatdlkeiakklltyvsisspnlterqladyy
ladpeiykktvealpsekrldsdgnrlseselynnavdsvptsqlnytedekkeiylfsq
lnavgnfatgtiatdplndsqvaviasiskempgisistswdrkiletslssivgsvsse
kaglpaeeaesylkkgyslndrvgtsylekqyeevlqgkrpvkeihldkhgdmesvenie
egskgknikltidlafqdsvdallksyfnselgnggakysegvyavalnpqtgavlsmsg
lkhdlktgeltpdslgtvtnvfvpgsvvkaatissgwengvlsgnqtltdqpivfqgsap
iyswyklaygsfpitavealeyssnayvvqtalgimgqtyqpnmfvgtsnlesamgklrs
tfgeyglgsatgidlpdestglvpkeynfanfitnafgqfdnytpmqlaqyvatianngv
rlaphivegiydnndkgglgeliqaidtkeinkvnisesdmailhqgfyqvshgtspltt
grafsdgatvsisgktgtgesyvaggqeatntnavayaptenpqiavavvfphntnltkn
vgpaiardiinlynqhhpmn

    Sequence, based on observed residues (ATOM records):
    >2wadB (B:)
tkvttssargeiydasgkplventlkqvvsftrsnkmtatdlkeiakklltyvsisspnl
terqladyyladpeiykktvealpseselynnavdsvptsqlnytedekkeiylfsqlna
vgnfatgtiatdplndsqvaviasiskempgisistswdrkiletslssivgsvssekag
lpaeeaesylkkgyslndrvgtsylekqyeevlqgkrpvkeihldkhgdmesvenieegs
kgknikltidlafqdsvdallksyfnselgnggakysegvyavalnpqtgavlsmsglkh
dlktgeltpdslgtvtnvfvpgsvvkaatissgwengvlsgnqtltdqpivfqgsapiys
wyklaygsfpitavealeyssnayvvqtalgimgqtyqpnmfvgtsnlesamgklrstfg
eyglgsatgidlpdestglvpkeynfanfitnafgqfdnytpmqlaqyvatianngvrla
phivegiydnndkgglgeliqaidtkeinkvnisesdmailhqgfyqvshgtsplttgra
fsdgatvsisgktgtntnavayaptenpqiavavvfphntnltknvgpaiardiinlynq
hhpmn

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2wadC (C:)
mrkfnshsipirlnllfsivillfmtiigrllymqvlnkdfyekklasasqtkvttssar
geiydasgkplventlkqvvsftrsnkmtatdlkeiakklltyvsisspnlterqladyy
ladpeiykktvealpsekrldsdgnrlseselynnavdsvptsqlnytedekkeiylfsq
lnavgnfatgtiatdplndsqvaviasiskempgisistswdrkiletslssivgsvsse
kaglpaeeaesylkkgyslndrvgtsylekqyeevlqgkrpvkeihldkhgdmesvenie
egskgknikltidlafqdsvdallksyfnselgnggakysegvyavalnpqtgavlsmsg
lkhdlktgeltpdslgtvtnvfvpgsvvkaatissgwengvlsgnqtltdqpivfqgsap
iyswyklaygsfpitavealeyssnayvvqtalgimgqtyqpnmfvgtsnlesamgklrs
tfgeyglgsatgidlpdestglvpkeynfanfitnafgqfdnytpmqlaqyvatianngv
rlaphivegiydnndkgglgeliqaidtkeinkvnisesdmailhqgfyqvshgtspltt
grafsdgatvsisgktgtgesyvaggqeatntnavayaptenpqiavavvfphntnltkn
vgpaiardiinlynqhhpmn

    Sequence, based on observed residues (ATOM records):
    >2wadC (C:)
sqtkvttssargeiydasgkplventlkqvvsftrsnkmtatdlkeiakklltyvsissp
nlterqladyyladpeiykktvealpseselynnavdsvptsqlnytedekkeiylfsql
navgnfatgtiatdplndsqvaviasiskempgisistswdrkiletslssivgsvssek
aglpaeeaesylkkgyslndrvgtsylekqyeevlqgkrpvkeihldkhgdmesveniee
gskgknikltidlafqdsvdallksyfnselgnggakysegvyavalnpqtgavlsmsgl
khdlktgeltpdslgtvtnvfvpgsvvkaatissgwengvlsgnqtltdqpivfqgsapi
yswyklaygsfpitavealeyssnayvvqtalgimgqtyqpnmfvgtsnlesamgklrst
fgeyglgsatgidlpdestglvpkeynfanfitnafgqfdnytpmqlaqyvatianngvr
laphivegiydnndkgglgeliqaidtkeinkvnisesdmailhqgfyqvshgtsplttg
rafsdgatvsisgktgtntnavayaptenpqiavavvfphntnltknvgpaiardiinly
nqhhpmn