PDB entry 2wa1

View 2wa1 on RCSB PDB site
Description: structure of the methyltransferase domain from modoc virus, a flavivirus with no known vector (nkv)
Class: transferase
Keywords: transferase, transmembrane, envelope protein, virus replication, virion, membrane, flavivirus, modoc virus, 2'-o- methyltransferase, methyltransferase, n7-methyltransferase
Deposited on 2009-02-02, released 2009-08-04
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-08-04, with a file datestamp of 2009-07-31.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.194
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: non-structural protein 5
    Species: MODOC VIRUS [TaxId:64300]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WA1
      • engineered mutation (84)
      • engineered mutation (94)
      • engineered mutation (141)
      • engineered mutation (209)
    • Uniprot Q8QL64 (8-End)
    Domains in SCOPe 2.03: d2wa1a_
  • Chain 'B':
    Compound: non-structural protein 5
    Species: MODOC VIRUS [TaxId:64300]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WA1
      • engineered mutation (84)
      • engineered mutation (94)
      • engineered mutation (141)
      • engineered mutation (209)
    • Uniprot Q8QL64
    Domains in SCOPe 2.03: d2wa1b_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wa1A (A:)
mahhhhhhgicssaptlgeiwkrklnqldakefmayrrrfvvevdrnearealakgktnt
ghavsrgtaklawiderggvelkgtvvdlgcgrgswsyyaasqpnvrevkaytlgtsghe
kprlvetfgwnlitfkskvdvtkmepfqadtvlcdigesnptaaveasrtltvlnvisrw
leynqgcgfcvkvlnpyscdvlealmkmqarfggglirvplsrnsthemyfvsgiknnim
gnvtavsrqllkrmeeqggervvpdykfstgtrsnl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wa1A (A:)
gicssaptlgeiwkrklnqldakefmayrrrfvvsrgtaklawiderggvelkgtvvdlg
cgrgswsyyaasqpnvrevkaytlgtsghekprlvetfgwnlitfkskvdvtkmepfqad
tvlcdigesnptaaveasrtltvlnvisrwleynqgcgfcvkvlnpyscdvlealmkmqa
rfggglirvplsrnsthemyfvsgiknnimgnvtavsrqllkrmee

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wa1B (B:)
mahhhhhhgicssaptlgeiwkrklnqldakefmayrrrfvvevdrnearealakgktnt
ghavsrgtaklawiderggvelkgtvvdlgcgrgswsyyaasqpnvrevkaytlgtsghe
kprlvetfgwnlitfkskvdvtkmepfqadtvlcdigesnptaaveasrtltvlnvisrw
leynqgcgfcvkvlnpyscdvlealmkmqarfggglirvplsrnsthemyfvsgiknnim
gnvtavsrqllkrmeeqggervvpdykfstgtrsnl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wa1B (B:)
aptlgeiwkrklnqldakefmayrrrfvvevdrnearealakgktntghavsrgtaklaw
iderggvelkgtvvdlgcgrgswsyyaasqpnvrevkaytlgtsghekprlvetfgwnli
tfkskvdvtkmepfqadtvlcdigesnptaaveasrtltvlnvisrwleynqgcgfcvkv
lnpyscdvlealmkmqarfggglirvplsrnsthemyfvsgiknnimgnvtavsrqllkr
meeqggervvpdykfstgtrsn