PDB entry 2w98

View 2w98 on RCSB PDB site
Description: crystal structure of human zinc-binding alcohol dehydrogenase 1 (zadh1) in ternary complex with nadp and phenylbutazone
Deposited on 2009-01-22, released 2009-04-07
The last revision was dated 2013-12-04, with a file datestamp of 2013-11-29.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.159
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostaglandin reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N8N7 (1-349)
      • expression tag (0)
  • Chain 'B':
    Compound: Prostaglandin reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N8N7 (1-349)
      • expression tag (0)
      • expression tag (350-354)
  • Heterogens: NAP, P1Z, PO4, LMR, CL, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2w98A (A:)
mmivqrvvlnsrpgkngnpvaenfrmeevylpdninegqvqvrtlylsvdpymrcrmned
tgtdyitpwqlsqvvdgggigiieeskhtnltkgdfvtsfywpwqtkvildgnslekvdp
qlvdghlsyflgaigmpgltsligiqekghitagsnktmvvsgaagacgsvagqighflg
csrvvgicgthekcilltselgfdaainykkdnvaeqlrescpagvdvyfdnvggnisdt
visqmnenshiilcgqisqynkdvpyppplspaieaiqkernitrerflvlnykdkfepg
ilqlsqwfkegklkiketvinglenmgaafqsmmtggnigkqivciseeiaenlyfq

    Sequence, based on observed residues (ATOM records):
    >2w98A (A:)
mmivqrvvlnsrpgkngnpvaenfrmeevylpdninegqvqvrtlylsvdpymrcrmned
tgtdyitpwqlsqvvdgggigiieeskhtnltkgdfvtsfywpwqtkvildgnslekvdp
qlvdghlsyflgaigmpgltsligiqekghitsnktmvvsgaagacgsvagqighflgcs
rvvgicgthekcilltselgfdaainykkdnvaeqlrescpagvdvyfdnvggnisdtvi
sqmnenshiilcgqisqynkdvpyppplspaieaiqkernitrerflvlnykdkfepgil
qlsqwfkegklkiketvinglenmgaafqsmmtggnigkqivciseei

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2w98B (B:)
mmivqrvvlnsrpgkngnpvaenfrmeevylpdninegqvqvrtlylsvdpymrcrmned
tgtdyitpwqlsqvvdgggigiieeskhtnltkgdfvtsfywpwqtkvildgnslekvdp
qlvdghlsyflgaigmpgltsligiqekghitagsnktmvvsgaagacgsvagqighflg
csrvvgicgthekcilltselgfdaainykkdnvaeqlrescpagvdvyfdnvggnisdt
visqmnenshiilcgqisqynkdvpyppplspaieaiqkernitrerflvlnykdkfepg
ilqlsqwfkegklkiketvinglenmgaafqsmmtggnigkqivciseeiaenlyfq

    Sequence, based on observed residues (ATOM records):
    >2w98B (B:)
mmivqrvvlnsrpgkngnpvaenfrmeevylpdninegqvqvrtlylsvdpymrcrmned
tgtdyitpwqlsqvvdgggigiieeskhtnltkgdfvtsfywpwqtkvildgnslekvdp
qlvdghlsyflgaigmpgltsligiqekghitagsnktmvvsgaagacgsvagqighflg
csrvvgicgthekcilltselgfdaainykkdnvaeqlrescpagvdvyfdnvggnisdt
visqmnenshiilcgqisqynkdvpyppplspaieaiqkernitrerflvlnykdkfepg
ilqlsqwfkegklkiketvinglenmgaafqsmmtggnigkqivciseeiaenly