PDB entry 2w8k

View 2w8k on RCSB PDB site
Description: y-family DNA polymerase dpo4 bypassing n2-naphthyl-guanine adduct in syn orientation
Class: transferase/DNA
Keywords: DNA-directed DNA polymerase, DNA, dpo4, adduct, n2-alkyl, cytoplasm, magnesium, transferase, metal-binding, mutator protein, DNA replication, nucleotidyltransferase, complex, polymerase, DNA damage, DNA repair, DNA-binding, transferase/DNA
Deposited on 2009-01-16, released 2009-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-10, with a file datestamp of 2009-02-06.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.233
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase IV
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W8K (6-23)
    • Uniprot Q97W02 (6-End)
    Domains in SCOPe 2.08: d2w8ka1, d2w8ka2, d2w8ka3
  • Chain 'P':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap *tp*tp*cp*doc)-3'
  • Chain 'T':
    Compound: 5'-d(*tp*cp*ap*cp*n2gp*gp*ap*ap*tp*cp*cp *tp*tp*cp*cp*cp*cp*c)-3'
  • Heterogens: DGT, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w8kA (A:)
hhhhhhmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfg
vkagipiveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdk
vrdyreaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrl
ireldiadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeyn
epirtrvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedld
ivsrgrtfphgisketaysesvkllqkileederkirrigvrfskfieaigldkffdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2w8kA (A:)
hmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagi
piveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyr
eaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireld
iadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirt
rvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrg
rtfphgisketaysesvkllqkileederkirrigvrfskfie

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.