PDB entry 2w81

View 2w81 on RCSB PDB site
Description: structure of a complex between neisseria meningitidis factor h binding protein and ccps 6-7 of human complement factor h
Deposited on 2009-01-08, released 2009-03-03
The last revision was dated 2010-01-12, with a file datestamp of 2010-01-08.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.275
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: complement factor h
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08603 (Start-122)
      • variant (81)
  • Chain 'B':
    Compound: complement factor h
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08603 (Start-122)
      • variant (81)
  • Chain 'C':
    Compound: factor h binding protein
    Species: Neisseria meningitidis [TaxId:487]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JXV4 (Start-249)
    • PDB 2W81 (250-End)
  • Chain 'D':
    Compound: factor h binding protein
    Species: Neisseria meningitidis [TaxId:487]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JXV4 (Start-249)
    • PDB 2W81 (250-252)
  • Chain 'E':
    Compound: complement factor h
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08603 (Start-122)
      • variant (81)
  • Chain 'F':
    Compound: factor h binding protein
    Species: Neisseria meningitidis [TaxId:487]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JXV4 (Start-249)
    • PDB 2W81
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2w81A (A:)
tlkpcdypdikhgglyhenmrrpyfpvavgkyysyycdehfetpsgsywdhihctqdgws
pavpclrkcyfpylengynqnhgrkfvqgksidvachpgyalpkaqttvtcmengwsptp
rci

    Sequence, based on observed residues (ATOM records):
    >2w81A (A:)
cdypdikhgglyhenmrrpyfpvavgkyysyycdehfetpsgsywdhihctqdgwspavp
clrkcyfpylengynqnhgrkfvqgksidvachyalkaqtvtcmengwsptprci

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2w81B (B:)
tlkpcdypdikhgglyhenmrrpyfpvavgkyysyycdehfetpsgsywdhihctqdgws
pavpclrkcyfpylengynqnhgrkfvqgksidvachpgyalpkaqttvtcmengwsptp
rci

    Sequence, based on observed residues (ATOM records):
    >2w81B (B:)
kpcdypdikhgglyhenmrrpyfpvavgkyysyycdehfetpsgsywdhihctqdgwspa
vpclrkcyfpylengynqnhgrkfvqgksidvachpgyalpkaqttvtcmengwsptprc
i

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2w81C (C:)
ggvaadigagladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslnt
gklkndkvsrfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmva
krqfrigdiagehtsfdklpeggratyrgtafgsddaggkltytidfaakqgngkiehlk
spelnvdlaaadikpdgkrhavisgsvlynqaekgsyslgifggkaqevagsaevktvng
irhiglaakqele

    Sequence, based on observed residues (ATOM records):
    >2w81C (C:)
gladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslntgklkndkvs
rfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmvakrqfrigdi
agehtsfdklpeggratyrgtafgsddaggkltytidfaakqgngkiehlkspelnvdla
aadikpdgkrhavisgsvlynqaekgsyslgifggkaqevagsaevktvngirhiglaak
qe

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2w81D (D:)
ggvaadigagladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslnt
gklkndkvsrfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmva
krqfrigdiagehtsfdklpeggratyrgtafgsddaggkltytidfaakqgngkiehlk
spelnvdlaaadikpdgkrhavisgsvlynqaekgsyslgifggkaqevagsaevktvng
irhiglaakqele

    Sequence, based on observed residues (ATOM records):
    >2w81D (D:)
gladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslntgklkndkvs
rfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmvakrqfrigdi
agehtsfdklpeggratyrgtafgsddaggkltytidfaakqgngkiehlkspelnvdla
aadikpdgkrhavisgsvlynqaekgsyslgifggkaqevagsaevktvnirhiglaakq
ele

  • Chain 'E':
    Sequence, based on SEQRES records:
    >2w81E (E:)
tlkpcdypdikhgglyhenmrrpyfpvavgkyysyycdehfetpsgsywdhihctqdgws
pavpclrkcyfpylengynqnhgrkfvqgksidvachpgyalpkaqttvtcmengwsptp
rci

    Sequence, based on observed residues (ATOM records):
    >2w81E (E:)
lkpcdypdikhgglyhenmrrpyfpvavgkyysyycdehfetpsgsywdhihctqdgwsp
avpclrkcyfpylengynqnhgrkfvqgksidvachpgyalpkaqttvtcmengwsptpr
ci

  • Chain 'F':
    Sequence, based on SEQRES records:
    >2w81F (F:)
ggvaadigagladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslnt
gklkndkvsrfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmva
krqfrigdiagehtsfdklpeggratyrgtafgsddaggkltytidfaakqgngkiehlk
spelnvdlaaadikpdgkrhavisgsvlynqaekgsyslgifggkaqevagsaevktvng
irhiglaakqele

    Sequence, based on observed residues (ATOM records):
    >2w81F (F:)
gladaltaldhkdkglqsltldqsvrkneklklaaqgaektygngdslntgklkndkvsr
fdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmvakrqfrigdia
gehtsfdklpeggratyrgtafgsddaggkltytidfaakqgngkiehlkspelnvdlaa
adikpdgkrhavisgsvlynqaekgsyslgifggkaqevagsaevktvngirhiglaakq