PDB entry 2w7o

View 2w7o on RCSB PDB site
Description: structure and activity of bypass synthesis by human dna polymerase kappa opposite the 7,8-dihydro-8-oxodeoxyguanosine adduct
Deposited on 2008-12-23, released 2009-06-16
The last revision was dated 2009-08-25, with a file datestamp of 2009-08-21.
Experiment type: XRAY
Resolution: 3.16 Å
R-factor: 0.241
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase kappa
    Species: Homo sapiens [TaxId:9606]
    Gene: POLK, DINB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA polymerase kappa
    Species: Homo sapiens [TaxId:9606]
    Gene: POLK, DINB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap*tp*tp*c)-3'
  • Chain 'F':
    Compound: 5'-d(tp*cp*ap*cp*8ogp*gp*ap*ap*tp*cp*cp*tp* tp*cp*cp*cp*cp*c)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap*tp*tp*c)-3'
  • Chain 'T':
    Compound: 5'-d(tp*cp*ap*cp*8ogp*gp*ap*ap*tp*cp*cp*tp* tp*cp*cp*cp*cp*c)-3'
  • Heterogens: DGT, CA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2w7oA (A:)
mglndnkagmegldkekinkiimeatkgsrfygnelkkekqvnqrienmmqqkaqitsqq
lrkaqlqvdrfameleqsrnlsntivhidmdafyaavemrdnpelkdkpiavgsmsmlst
snyharrfgvraampgfiakrlcpqliivppnfdkyravskevkeiladydpnfmamsld
eaylnitkhleerqnwpedkrryfikmgssvendnpgkevnklsehersispllfeesps
dvqppgdpfqvnfeeqnnpqilqnsvvfgtsaqevvkeirfrieqkttltasagiapntm
lakvcsdknkpngqyqilpnrqavmdfikdlpirkvsgigkvtekmlkalgiitctelyq
qrallsllfsetswhyflhislglgsthltrdgerksmsvertfseinkaeeqyslcqel
cselaqdlqkerlkgrtvtiklknvnfevktrastvssvvstaeeifaiakellkteida
dfphplrlrlmgvrissfpneedrkhqq

    Sequence, based on observed residues (ATOM records):
    >2w7oA (A:)
kekinkiimeatkgsrfygnelkkekqvnqrienmmqqkaqitsqqlrkaqlqvdrfame
leqsrnlsntivhidmdafyaavemrdnpelkdkpiavgsmsmlstsnyharrfgvraam
pgfiakrlcpqliivppnfdkyravskevkeiladydpnfmamsldeaylnitkhleerq
nwpedkrryfikqnsvvfgtsaqevvkeirfrieqkttltasagiapntmlakvcsdknk
pngqyqilpnrqavmdfikdlpirkvsgigkvtekmlkalgiitctelyqqrallsllfs
etswhyflhislglgsthltrdgerksmsvertfseinkaeeqyslcqelcselaqdlqk
erlkgrtvtiklknvnfevktrastvssvvstaeeifaiakellkteidadfphplrlrl
mgvrissfpnee

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2w7oB (B:)
mglndnkagmegldkekinkiimeatkgsrfygnelkkekqvnqrienmmqqkaqitsqq
lrkaqlqvdrfameleqsrnlsntivhidmdafyaavemrdnpelkdkpiavgsmsmlst
snyharrfgvraampgfiakrlcpqliivppnfdkyravskevkeiladydpnfmamsld
eaylnitkhleerqnwpedkrryfikmgssvendnpgkevnklsehersispllfeesps
dvqppgdpfqvnfeeqnnpqilqnsvvfgtsaqevvkeirfrieqkttltasagiapntm
lakvcsdknkpngqyqilpnrqavmdfikdlpirkvsgigkvtekmlkalgiitctelyq
qrallsllfsetswhyflhislglgsthltrdgerksmsvertfseinkaeeqyslcqel
cselaqdlqkerlkgrtvtiklknvnfevktrastvssvvstaeeifaiakellkteida
dfphplrlrlmgvrissfpneedrkhqq

    Sequence, based on observed residues (ATOM records):
    >2w7oB (B:)
kekinkiimeatkgsrfygnelkkekqvnqrienmmqqkaqitsqqlrkaqlqvdrfame
leqsrnlsntivhidmdafyaavemrdnpelkdkpiavgsmsmlstsnyharrfgvraam
pgfiakrlcpqliivppnfdkyravskevkeiladydpnfmamsldeaylnitkhleerq
nwpedkrryfinsvvfgtsaqevvkeirfrieqkttltasagiapntmlakvcsdknkpn
gqyqilpnrqavmdfikdlpirkvsgigkvtekmlkalgiitctelyqqrallsllfset
swhyflhislglgsthltrdgerksmsvertfseinkaeeqyslcqelcselaqdlqker
lkgrtvtiklknvnfevktrastvssvvstaeeifaiakellkteidadfphplrlrlmg
vrissfpnee

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.