PDB entry 2w6o

View 2w6o on RCSB PDB site
Description: crystal structure of biotin carboxylase from e. coli in complex with 4-amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment
Class: ligase
Keywords: ligase, ATP-binding, fatty acid biosynthesis, nucleotide-binding, lipid synthesis, ATP-grasp domain, fragment screening
Deposited on 2008-12-18, released 2009-05-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-04-27, with a file datestamp of 2011-04-22.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.234
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: biotin carboxylase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2w6oa1, d2w6oa2, d2w6oa3
  • Chain 'C':
    Compound: biotin carboxylase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2w6oc1, d2w6oc2, d2w6oc3
  • Heterogens: OA3, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w6oA (A:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklglqek

    Sequence, based on observed residues (ATOM records): (download) 
    >2w6oA (A:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2w6oC (C:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklglqek

    Sequence, based on observed residues (ATOM records): (download) 
    >2w6oC (C:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklgl