PDB entry 2w5y

View 2w5y on RCSB PDB site
Description: binary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine.
Deposited on 2008-12-15, released 2009-02-10
The last revision was dated 2009-02-10, with a file datestamp of 2009-02-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.191
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: histone-lysine n-methyltransferase hrx
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W5Y
    • Uniprot Q03164 (Start-191)
  • Heterogens: ZN, SAH, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2w5yA (A:)
    gplgshmhrqppeynpndeeeeevqlksarratsmdlpmpmrfrhlkktskeavgvyrsp
    ihgrglfckrnidagemvieyagnvirsiqtdkrekyydskgigcymfriddsevvdatm
    hgnaarfinhscepncysrvinidgqkhivifamrkiyrgeeltydykfpiedasnklpc
    ncgakkcrkfln
    

    Sequence, based on observed residues (ATOM records):
    >2w5yA (A:)
    pndeeeeevqlksarratsmdlpmpmrfrhlkktskeavgvyrspihgrglfckrnidag
    emvieyagnvirsiqtdkrekyydskgigcymfriddsevvdatmhgnaarfinhscepn
    cysrvinidgqkhivifamrkiyrgeeltydykfklpcncgakkcrkfln