PDB entry 2w5h
View 2w5h on RCSB PDB site
Description: human nek2 kinase apo
Class: transferase
Keywords: ser/thr protein kinase, kinase, nucleus, meiosis, mitosis, cytoplasm, serine/threonine-protein kinase, metal-binding, phosphoprotein, nucleotide-binding, magnesium, cell cycle, ATP-binding, transferase, centrosome splitting, alternative splicing, coiled coil, polymorphism, cell division
Deposited on
2008-12-10, released
2008-12-23
The last revision prior to the SCOPe 2.05 freeze date was dated
2009-09-01, with a file datestamp of
2009-08-28.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: 0.197
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: serine/threonine-protein kinase nek2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P51955 (Start-270)
- engineered mutation (174)
- PDB 2W5H (271-278)
Domains in SCOPe 2.05: d2w5ha_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2w5hA (A:)
mpsraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllr
elkhpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtql
tlalkechrrsdgghtvlhrdlkpanvfldgkqnvklgdfglarilnhdtsfakafvgtp
yymspeqmnrmsyneksdiwslgcllyelcalmppftafsqkelagkiregkfrripyry
sdelneiitrmlnlkdyhrpsveeilenplilehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2w5hA (A:)
sraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllrel
khpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtqltl
alkechrrshrdlkpanvfldgkqnvklgdfglarhdtsfakafvgtpyymspeqmnsyn
eksdiwslgcllyelcalmppftafsqkelagkiregkfrripyrysdelneiitrmlnl
kdyhrpsveeilenplilehhhhhh