PDB entry 2w54

View 2w54 on RCSB PDB site
Description: crystal structure of xanthine dehydrogenase from rhodobacter capsulatus in complex with bound inhibitor pterin-6-aldehyde
Deposited on 2008-12-04, released 2008-12-23
The last revision was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Xanthine Dehydrogenase
    Species: RHODOBACTER CAPSULATUS [TaxId:1061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54050 (0-461)
      • conflict (25)
  • Chain 'B':
    Compound: Xanthine Dehydrogenase
    Species: RHODOBACTER CAPSULATUS [TaxId:1061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54051 (Start-776)
      • conflict (771)
  • Chain 'C':
    Compound: Xanthine Dehydrogenase
    Species: RHODOBACTER CAPSULATUS [TaxId:1061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54050 (0-461)
      • conflict (25)
  • Chain 'D':
    Compound: Xanthine Dehydrogenase
    Species: RHODOBACTER CAPSULATUS [TaxId:1061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54051 (Start-776)
      • conflict (771)
  • Chain 'E':
    Compound: Xanthine Dehydrogenase
    Species: RHODOBACTER CAPSULATUS [TaxId:1061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54050 (0-461)
      • conflict (25)
  • Chain 'F':
    Compound: Xanthine Dehydrogenase
    Species: RHODOBACTER CAPSULATUS [TaxId:1061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54051 (Start-776)
      • conflict (771)
  • Chain 'G':
    Compound: Xanthine Dehydrogenase
    Species: RHODOBACTER CAPSULATUS [TaxId:1061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54050 (0-461)
      • conflict (25)
  • Chain 'H':
    Compound: Xanthine Dehydrogenase
    Species: RHODOBACTER CAPSULATUS [TaxId:1061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54051 (Start-776)
      • conflict (771)
  • Heterogens: FES, FAD, XAX, BA, HHR

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2w54A (A:)
meiafllngetrrvriedptqsllewlraegltgtkegcnegdcgactvmirdaagsrav
naclmmlpqiagkalrtiegiaapdgrlhpvqqamidhhgsqcgfctpgfivsmaaahdr
drkdyddllagnlcrctgyapilraaeaaageppadwlqadaaftlaqlssgvrgqtapa
flpetsdaladwylahpeatliaggtdvslwvtkalrdlpevaflshckdlaqiretpdg
ygigagvtiaalrafaegphpalagllrrfaseqvrqvatiggniangspigdgppalia
mgasltlrrgqerrrmpledffleyrkqdrrpgefvesvtlpksapglrcyklskrfdqd
isavcgclnltlkgskietariafggmagvpkraaafeaaligqdfredtiaaalpllaq
dftplsdmrasaayrmnaaqamalryvrelsgeavavlevmp

    Sequence, based on observed residues (ATOM records):
    >2w54A (A:)
meiafllngetrrvriedptqsllewlraegltgtkegcnegdcgactvmirdaagsrav
naclmmlpqiagkalrtiegiaapdgrlhpvqqamidhhgsqcgfctpgfivsmaaahdr
drkdyddllagnlcrctgyapilraaeaaageppadwlqadaaftlpaflpetsdaladw
ylahpeatliaggtdvslwvtkalrdlpevaflshckdlaqiretpdgygigagvtiaal
rafaegphpalagllrrfaseqvrqvatiggniangspigdgppaliamgasltlrrgqe
rrrmpledffleyrkqdrrpgefvesvtlpksapglrcyklskrfdqdisavcgclnltl
kgskietariafggmagvpkraaafeaaligqdfredtiaaalpllaqdftplsdmrasa
ayrmnaaqamalryvrelsgeavavlevmp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2w54B (B:)
msvgkplphdsarahvtgqarylddlpcpantlhlafglsteasaaitgldlepvrespg
viavftaadlphdndaspapspepvlatgevhfvgqpiflvaatshraariaarkarity
aprpailtldqalaadsrfeggpviwargdvetalagaahlaegcfeiggqehfylegqa
alalpaeggvvihcssqhpseiqhkvahalglafhdvrvemrrmgggfggkesqgnhlai
acavaaratgrpckmrydrdddmvitgkrhdfriryrigadasgkllgadfvhlarcgws
adlslpvcdramlhadgsyfvpalrieshrlrtntqsntafrgfggpqgalgmeraiehl
argmgrdpaelralnfydppergglsappsppepiatkktqtthygqevadcvlgelvtr
lqksanfttrraeiaawnstnrtlargialspvkfgisftlthlnqagalvqiytdgsva
lnhggtemgqglhakmvqvaaavlgidpvqvritatdtskvpntsataassgadmngmav
kdacetlrgrlagfvaaregcaardvifdagqvqasgkswrfaeivaaaymarislsatg
fyatpklswdrlrgqgrpflyfaygaaitevvidrltgenrilrtdilhdagaslnpald
igqiegayvqgagwltteelvwdhcgrlmthapstykipafsdrprifnvalwdqpnree
tifrskavgeppfllgisaflalhdacaacgphwpdlqapatpeavlaavrraegra

    Sequence, based on observed residues (ATOM records):
    >2w54B (B:)
svgkplphdsarahvtgqarylddlpcpantlhlafglsteasaaitgldlepvrespgv
iavftaadlphdndaspapspepvlatgevhfvgqpiflvaatshraariaarkaritya
prpailtldqalaadsrfeggpviwargdvetalagaahlaegcfeiggqehfylegqaa
lalpaeggvvihcssqhpseiqhkvahalglafhdvrvemrrmgggfggkesqgnhlaia
cavaaratgrpckmrydrdddmvitgkrhdfriryrigadasgkllgadfvhlarcgwsa
dlslpvcdramlhadgsyfvpalrieshrlrtntqsntafrgfggpqgalgmeraiehla
rgmgrdpaelralnfydppekktqtthygqevadcvlgelvtrlqksanfttrraeiaaw
nstnrtlargialspvkfgisftlthlnqagalvqiytdgsvalnhggtemgqglhakmv
qvaaavlgidpvqvritatdtskvpntsataassgadmngmavkdacetlrgrlagfvaa
regcaardvifdagqvqasgkswrfaeivaaaymarislsatgfyatpklswdrlrgqgr
pflyfaygaaitevvidrltgenrilrtdilhdagaslnpaldigqiegayvqgagwltt
eelvwdhcgrlmthapstykipafsdrprifnvalwdqpnreetifrskavgeppfllgi
saflalhdacaacgphwpdlqapatpeavlaavrraegra

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2w54C (C:)
meiafllngetrrvriedptqsllewlraegltgtkegcnegdcgactvmirdaagsrav
naclmmlpqiagkalrtiegiaapdgrlhpvqqamidhhgsqcgfctpgfivsmaaahdr
drkdyddllagnlcrctgyapilraaeaaageppadwlqadaaftlaqlssgvrgqtapa
flpetsdaladwylahpeatliaggtdvslwvtkalrdlpevaflshckdlaqiretpdg
ygigagvtiaalrafaegphpalagllrrfaseqvrqvatiggniangspigdgppalia
mgasltlrrgqerrrmpledffleyrkqdrrpgefvesvtlpksapglrcyklskrfdqd
isavcgclnltlkgskietariafggmagvpkraaafeaaligqdfredtiaaalpllaq
dftplsdmrasaayrmnaaqamalryvrelsgeavavlevmp

    Sequence, based on observed residues (ATOM records):
    >2w54C (C:)
meiafllngetrrvriedptqsllewlraegltgtkegcnegdcgactvmirdaagsrav
naclmmlpqiagkalrtiegiaapdgrlhpvqqamidhhgsqcgfctpgfivsmaaahdr
drkdyddllagnlcrctgyapilraaeaaageppadwlqadaaftlpaflpetsdaladw
ylahpeatliaggtdvslwvtkalrdlpevaflshckdlaqiretpdgygigagvtiaal
rafaegphpalagllrrfaseqvrqvatiggniangspigdgppaliamgasltlrrgqe
rrrmpledffleyrkqdrrpgefvesvtlpksapglrcyklskrfdqdisavcgclnltl
kgskietariafggmagvpkraaafeaaligqdfredtiaaalpllaqdftplsdmrasa
ayrmnaaqamalryvrelsgeavavlevmp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2w54D (D:)
msvgkplphdsarahvtgqarylddlpcpantlhlafglsteasaaitgldlepvrespg
viavftaadlphdndaspapspepvlatgevhfvgqpiflvaatshraariaarkarity
aprpailtldqalaadsrfeggpviwargdvetalagaahlaegcfeiggqehfylegqa
alalpaeggvvihcssqhpseiqhkvahalglafhdvrvemrrmgggfggkesqgnhlai
acavaaratgrpckmrydrdddmvitgkrhdfriryrigadasgkllgadfvhlarcgws
adlslpvcdramlhadgsyfvpalrieshrlrtntqsntafrgfggpqgalgmeraiehl
argmgrdpaelralnfydppergglsappsppepiatkktqtthygqevadcvlgelvtr
lqksanfttrraeiaawnstnrtlargialspvkfgisftlthlnqagalvqiytdgsva
lnhggtemgqglhakmvqvaaavlgidpvqvritatdtskvpntsataassgadmngmav
kdacetlrgrlagfvaaregcaardvifdagqvqasgkswrfaeivaaaymarislsatg
fyatpklswdrlrgqgrpflyfaygaaitevvidrltgenrilrtdilhdagaslnpald
igqiegayvqgagwltteelvwdhcgrlmthapstykipafsdrprifnvalwdqpnree
tifrskavgeppfllgisaflalhdacaacgphwpdlqapatpeavlaavrraegra

    Sequence, based on observed residues (ATOM records):
    >2w54D (D:)
svgkplphdsarahvtgqarylddlpcpantlhlafglsteasaaitgldlepvrespgv
iavftaadlphdndaspapspepvlatgevhfvgqpiflvaatshraariaarkaritya
prpailtldqalaadsrfeggpviwargdvetalagaahlaegcfeiggqehfylegqaa
lalpaeggvvihcssqhpseiqhkvahalglafhdvrvemrrmgggfggkesqgnhlaia
cavaaratgrpckmrydrdddmvitgkrhdfriryrigadasgkllgadfvhlarcgwsa
dlslpvcdramlhadgsyfvpalrieshrlrtntqsntafrgfggpqgalgmeraiehla
rgmgrdpaelralnfydppekktqtthygqevadcvlgelvtrlqksanfttrraeiaaw
nstnrtlargialspvkfgisftlthlnqagalvqiytdgsvalnhggtemgqglhakmv
qvaaavlgidpvqvritatdtskvpntsataassgadmngmavkdacetlrgrlagfvaa
regcaardvifdagqvqasgkswrfaeivaaaymarislsatgfyatpklswdrlrgqgr
pflyfaygaaitevvidrltgenrilrtdilhdagaslnpaldigqiegayvqgagwltt
eelvwdhcgrlmthapstykipafsdrprifnvalwdqpnreetifrskavgeppfllgi
saflalhdacaacgphwpdlqapatpeavlaavrraegra

  • Chain 'E':
    Sequence, based on SEQRES records:
    >2w54E (E:)
meiafllngetrrvriedptqsllewlraegltgtkegcnegdcgactvmirdaagsrav
naclmmlpqiagkalrtiegiaapdgrlhpvqqamidhhgsqcgfctpgfivsmaaahdr
drkdyddllagnlcrctgyapilraaeaaageppadwlqadaaftlaqlssgvrgqtapa
flpetsdaladwylahpeatliaggtdvslwvtkalrdlpevaflshckdlaqiretpdg
ygigagvtiaalrafaegphpalagllrrfaseqvrqvatiggniangspigdgppalia
mgasltlrrgqerrrmpledffleyrkqdrrpgefvesvtlpksapglrcyklskrfdqd
isavcgclnltlkgskietariafggmagvpkraaafeaaligqdfredtiaaalpllaq
dftplsdmrasaayrmnaaqamalryvrelsgeavavlevmp

    Sequence, based on observed residues (ATOM records):
    >2w54E (E:)
meiafllngetrrvriedptqsllewlraegltgtkegcnegdcgactvmirdaagsrav
naclmmlpqiagkalrtiegiaapdgrlhpvqqamidhhgsqcgfctpgfivsmaaahdr
drkdyddllagnlcrctgyapilraaeaaageppadwlqadaaftlpaflpetsdaladw
ylahpeatliaggtdvslwvtkalrdlpevaflshckdlaqiretpdgygigagvtiaal
rafaegphpalagllrrfaseqvrqvatiggniangspigdgppaliamgasltlrrgqe
rrrmpledffleyrkqdrrpgefvesvtlpksapglrcyklskrfdqdisavcgclnltl
kgskietariafggmagvpkraaafeaaligqdfredtiaaalpllaqdftplsdmrasa
ayrmnaaqamalryvrelsgeavavlevmp

  • Chain 'F':
    Sequence, based on SEQRES records:
    >2w54F (F:)
msvgkplphdsarahvtgqarylddlpcpantlhlafglsteasaaitgldlepvrespg
viavftaadlphdndaspapspepvlatgevhfvgqpiflvaatshraariaarkarity
aprpailtldqalaadsrfeggpviwargdvetalagaahlaegcfeiggqehfylegqa
alalpaeggvvihcssqhpseiqhkvahalglafhdvrvemrrmgggfggkesqgnhlai
acavaaratgrpckmrydrdddmvitgkrhdfriryrigadasgkllgadfvhlarcgws
adlslpvcdramlhadgsyfvpalrieshrlrtntqsntafrgfggpqgalgmeraiehl
argmgrdpaelralnfydppergglsappsppepiatkktqtthygqevadcvlgelvtr
lqksanfttrraeiaawnstnrtlargialspvkfgisftlthlnqagalvqiytdgsva
lnhggtemgqglhakmvqvaaavlgidpvqvritatdtskvpntsataassgadmngmav
kdacetlrgrlagfvaaregcaardvifdagqvqasgkswrfaeivaaaymarislsatg
fyatpklswdrlrgqgrpflyfaygaaitevvidrltgenrilrtdilhdagaslnpald
igqiegayvqgagwltteelvwdhcgrlmthapstykipafsdrprifnvalwdqpnree
tifrskavgeppfllgisaflalhdacaacgphwpdlqapatpeavlaavrraegra

    Sequence, based on observed residues (ATOM records):
    >2w54F (F:)
svgkplphdsarahvtgqarylddlpcpantlhlafglsteasaaitgldlepvrespgv
iavftaadlphdndaspapspepvlatgevhfvgqpiflvaatshraariaarkaritya
prpailtldqalaadsrfeggpviwargdvetalagaahlaegcfeiggqehfylegqaa
lalpaeggvvihcssqhpseiqhkvahalglafhdvrvemrrmgggfggkesqgnhlaia
cavaaratgrpckmrydrdddmvitgkrhdfriryrigadasgkllgadfvhlarcgwsa
dlslpvcdramlhadgsyfvpalrieshrlrtntqsntafrgfggpqgalgmeraiehla
rgmgrdpaelralnfydppekktqtthygqevadcvlgelvtrlqksanfttrraeiaaw
nstnrtlargialspvkfgisftlthlnqagalvqiytdgsvalnhggtemgqglhakmv
qvaaavlgidpvqvritatdtskvpntsataassgadmngmavkdacetlrgrlagfvaa
regcaardvifdagqvqasgkswrfaeivaaaymarislsatgfyatpklswdrlrgqgr
pflyfaygaaitevvidrltgenrilrtdilhdagaslnpaldigqiegayvqgagwltt
eelvwdhcgrlmthapstykipafsdrprifnvalwdqpnreetifrskavgeppfllgi
saflalhdacaacgphwpdlqapatpeavlaavrraegra

  • Chain 'G':
    Sequence, based on SEQRES records:
    >2w54G (G:)
meiafllngetrrvriedptqsllewlraegltgtkegcnegdcgactvmirdaagsrav
naclmmlpqiagkalrtiegiaapdgrlhpvqqamidhhgsqcgfctpgfivsmaaahdr
drkdyddllagnlcrctgyapilraaeaaageppadwlqadaaftlaqlssgvrgqtapa
flpetsdaladwylahpeatliaggtdvslwvtkalrdlpevaflshckdlaqiretpdg
ygigagvtiaalrafaegphpalagllrrfaseqvrqvatiggniangspigdgppalia
mgasltlrrgqerrrmpledffleyrkqdrrpgefvesvtlpksapglrcyklskrfdqd
isavcgclnltlkgskietariafggmagvpkraaafeaaligqdfredtiaaalpllaq
dftplsdmrasaayrmnaaqamalryvrelsgeavavlevmp

    Sequence, based on observed residues (ATOM records):
    >2w54G (G:)
meiafllngetrrvriedptqsllewlraegltgtkegcnegdcgactvmirdaagsrav
naclmmlpqiagkalrtiegiaapdgrlhpvqqamidhhgsqcgfctpgfivsmaaahdr
drkdyddllagnlcrctgyapilraaeaaageppadwlqadaaftlpaflpetsdaladw
ylahpeatliaggtdvslwvtkalrdlpevaflshckdlaqiretpdgygigagvtiaal
rafaegphpalagllrrfaseqvrqvatiggniangspigdgppaliamgasltlrrgqe
rrrmpledffleyrkqdrrpgefvesvtlpksapglrcyklskrfdqdisavcgclnltl
kgskietariafggmagvpkraaafeaaligqdfredtiaaalpllaqdftplsdmrasa
ayrmnaaqamalryvrelsgeavavlevmp

  • Chain 'H':
    Sequence, based on SEQRES records:
    >2w54H (H:)
msvgkplphdsarahvtgqarylddlpcpantlhlafglsteasaaitgldlepvrespg
viavftaadlphdndaspapspepvlatgevhfvgqpiflvaatshraariaarkarity
aprpailtldqalaadsrfeggpviwargdvetalagaahlaegcfeiggqehfylegqa
alalpaeggvvihcssqhpseiqhkvahalglafhdvrvemrrmgggfggkesqgnhlai
acavaaratgrpckmrydrdddmvitgkrhdfriryrigadasgkllgadfvhlarcgws
adlslpvcdramlhadgsyfvpalrieshrlrtntqsntafrgfggpqgalgmeraiehl
argmgrdpaelralnfydppergglsappsppepiatkktqtthygqevadcvlgelvtr
lqksanfttrraeiaawnstnrtlargialspvkfgisftlthlnqagalvqiytdgsva
lnhggtemgqglhakmvqvaaavlgidpvqvritatdtskvpntsataassgadmngmav
kdacetlrgrlagfvaaregcaardvifdagqvqasgkswrfaeivaaaymarislsatg
fyatpklswdrlrgqgrpflyfaygaaitevvidrltgenrilrtdilhdagaslnpald
igqiegayvqgagwltteelvwdhcgrlmthapstykipafsdrprifnvalwdqpnree
tifrskavgeppfllgisaflalhdacaacgphwpdlqapatpeavlaavrraegra

    Sequence, based on observed residues (ATOM records):
    >2w54H (H:)
svgkplphdsarahvtgqarylddlpcpantlhlafglsteasaaitgldlepvrespgv
iavftaadlphdndaspapspepvlatgevhfvgqpiflvaatshraariaarkaritya
prpailtldqalaadsrfeggpviwargdvetalagaahlaegcfeiggqehfylegqaa
lalpaeggvvihcssqhpseiqhkvahalglafhdvrvemrrmgggfggkesqgnhlaia
cavaaratgrpckmrydrdddmvitgkrhdfriryrigadasgkllgadfvhlarcgwsa
dlslpvcdramlhadgsyfvpalrieshrlrtntqsntafrgfggpqgalgmeraiehla
rgmgrdpaelralnfydppekktqtthygqevadcvlgelvtrlqksanfttrraeiaaw
nstnrtlargialspvkfgisftlthlnqagalvqiytdgsvalnhggtemgqglhakmv
qvaaavlgidpvqvritatdtskvpntsataassgadmngmavkdacetlrgrlagfvaa
regcaardvifdagqvqasgkswrfaeivaaaymarislsatgfyatpklswdrlrgqgr
pflyfaygaaitevvidrltgenrilrtdilhdagaslnpaldigqiegayvqgagwltt
eelvwdhcgrlmthapstykipafsdrprifnvalwdqpnreetifrskavgeppfllgi
saflalhdacaacgphwpdlqapatpeavlaavrraegra