PDB entry 2w4m

View 2w4m on RCSB PDB site
Description: The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP
Class: hydrolase
Keywords: n-acetylneuraminate, neu5ac-9- phosphate, carbohydrate metabolism, n-acetylneuraminic acid phosphatase, nanp, hdhd4, hydrolase, magnesium, sialic acid
Deposited on 2008-11-28, released 2008-12-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: n-acylneuraminate-9-phosphatase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W4M (Start-21)
    • Uniprot Q8TBE9 (22-End)
    Domains in SCOPe 2.08: d2w4ma1, d2w4ma2
  • Heterogens: NA, CL, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w4mA (A:)
mhhhhhhssgvdlgtenlyfqsmglsrvravffdldntlidtagasrrgmlevikllqsk
yhykeeaeiicdkvqvklskecfhpyntcitdlrtshweeaiqetkggaanrklaeecyf
lwkstrlqhmtlaedvkamltelrkevrlllltngdrqtqrekieacacqsyfdavvvgg
eqreekpapsifyyccnllgvqpgdcvmvgdtletdiqgglnaglkatvwinkngivplk
sspvphymvssvlelpallqsidckvsmst

    Sequence, based on observed residues (ATOM records): (download) 
    >2w4mA (A:)
nlyfqsmglsrvravffdldntlidtagasrrgmlevikllqskyhykeeaeiicdkvqv
klskecfhpyntcitdlrtshweeaiqetkggaanrklaeecyflwkstrlqhmtlaedv
kamltelrkevrlllltngdrqtqrekieacacqsyfdavvvggeqreekpapsifyycc
nllgvqpgdcvmvgdtletdiqgglnaglkatvwinkngivplksspvphymvssvlelp
allqsidckv