PDB entry 2w40

View 2w40 on RCSB PDB site
Description: crystal structure of plasmodium falciparum glycerol kinase with bound glycerol
Class: transferase
Keywords: closed conformation, kinase, malaria, plasmodium, transferase, sugar kinase/hsp70/actin superfamily, glycerol kinase, open conformation
Deposited on 2008-11-18, released 2008-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-03, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: 0.171
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glycerol kinase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W40
    • Uniprot Q8IDI4 (2-502)
    Domains in SCOPe 2.08: d2w40a1, d2w40a2
  • Chain 'B':
    Compound: glycerol kinase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W40 (0-1)
    • Uniprot Q8IDI4 (2-502)
    Domains in SCOPe 2.08: d2w40b1, d2w40b2
  • Chain 'C':
    Compound: glycerol kinase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W40 (Start-1)
    • Uniprot Q8IDI4 (2-502)
    Domains in SCOPe 2.08: d2w40c1, d2w40c2
  • Chain 'D':
    Compound: glycerol kinase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W40 (0-1)
    • Uniprot Q8IDI4 (2-502)
    Domains in SCOPe 2.08: d2w40d1, d2w40d2
  • Heterogens: EDO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w40A (A:)
gsmnvilsidqstqstkvffydeelnivhsnnlnheqkclkpgwyehdpieimtnlynlm
negikvlkdkytsviikcigitnqretviiwdritgkplynaivwldtrveelvtefsak
ynnndiqkktgtyfntyfsafkilwliqnnpeikqkiddgtavignintwlifnltkgnc
ytdvtnasrtllmdintlqwdekmckifnitnmsvlpeiksncsnfglvksehvpdylni
pitgcigdqqsacigqaifdegeakctygtgvfllintgekvvystcglitticykfndn
dkpkyalegsigtagsgvswllknkliddpseasdimekcenttgvifvpafsglyaprw
rsdarasiygmtfntershivrallegiafqlneivdsltsdmgiemlhvlrcdggmtkn
kpfmqfnsdiintkievskykevtslgaavlaglevkiwdsldsvksllrrsdavfhskm
ddkkrkkktsewnkavertliql

    Sequence, based on observed residues (ATOM records): (download) 
    >2w40A (A:)
mnvilsidqstqstkvffydeelnivhsnnlnheqkclkpgwyehdpieimtnlynlmne
gikvlkdkytsviikcigitnqretviiwdritgkplynaivwldtrveelvtefsakyn
nndiqkktgtyfntyfsafkilwliqnnpeikqkiddgtavignintwlifnltkgncyt
dvtnasrtllmdintlqwdekmckifnitnmsvlpeiksncsnfglvksehvpdylnipi
tgcigdqqsacigqaifdegeakctygtgvfllintgekvvystcglitticykfndndk
pkyalegsigtagsgvswllknkliddpseasdimekcenttgvifvpafsglyaprwrs
darasiygmtfntershivrallegiafqlneivdsltsdmgiemlhvlrcdggmtknkp
fmqfnsdiintkievskykevtslgaavlaglevkiwdsldsvksllrrsdavfhskmdd
kkrkkktsewnkavertliql

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2w40B (B:)
gsmnvilsidqstqstkvffydeelnivhsnnlnheqkclkpgwyehdpieimtnlynlm
negikvlkdkytsviikcigitnqretviiwdritgkplynaivwldtrveelvtefsak
ynnndiqkktgtyfntyfsafkilwliqnnpeikqkiddgtavignintwlifnltkgnc
ytdvtnasrtllmdintlqwdekmckifnitnmsvlpeiksncsnfglvksehvpdylni
pitgcigdqqsacigqaifdegeakctygtgvfllintgekvvystcglitticykfndn
dkpkyalegsigtagsgvswllknkliddpseasdimekcenttgvifvpafsglyaprw
rsdarasiygmtfntershivrallegiafqlneivdsltsdmgiemlhvlrcdggmtkn
kpfmqfnsdiintkievskykevtslgaavlaglevkiwdsldsvksllrrsdavfhskm
ddkkrkkktsewnkavertliql

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2w40C (C:)
gsmnvilsidqstqstkvffydeelnivhsnnlnheqkclkpgwyehdpieimtnlynlm
negikvlkdkytsviikcigitnqretviiwdritgkplynaivwldtrveelvtefsak
ynnndiqkktgtyfntyfsafkilwliqnnpeikqkiddgtavignintwlifnltkgnc
ytdvtnasrtllmdintlqwdekmckifnitnmsvlpeiksncsnfglvksehvpdylni
pitgcigdqqsacigqaifdegeakctygtgvfllintgekvvystcglitticykfndn
dkpkyalegsigtagsgvswllknkliddpseasdimekcenttgvifvpafsglyaprw
rsdarasiygmtfntershivrallegiafqlneivdsltsdmgiemlhvlrcdggmtkn
kpfmqfnsdiintkievskykevtslgaavlaglevkiwdsldsvksllrrsdavfhskm
ddkkrkkktsewnkavertliql

    Sequence, based on observed residues (ATOM records): (download) 
    >2w40C (C:)
smnvilsidqstqstkvffydeelnivhsnnlnheqkclkpgwyehdpieimtnlynlmn
egikvlkdkytsviikcigitnqretviiwdritgkplynaivwldtrveelvtefsaky
nnndiqkktgtyfntyfsafkilwliqnnpeikqkiddgtavignintwlifnltkgncy
tdvtnasrtllmdintlqwdekmckifnitnmsvlpeiksncsnfglvksehvpdylnip
itgcigdqqsacigqaifdegeakctygtgvfllintgekvvystcglitticykfndnd
kpkyalegsigtagsgvswllknkliddpseasdimekcenttgvifvpafsglyaprwr
sdarasiygmtfntershivrallegiafqlneivdsltsdmgiemlhvlrcdggmtknk
pfmqfnsdiintkievskykevtslgaavlaglevkiwdsldsvksllrrsdavfhskmd
dkkrkkktsewnkavertliql

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2w40D (D:)
gsmnvilsidqstqstkvffydeelnivhsnnlnheqkclkpgwyehdpieimtnlynlm
negikvlkdkytsviikcigitnqretviiwdritgkplynaivwldtrveelvtefsak
ynnndiqkktgtyfntyfsafkilwliqnnpeikqkiddgtavignintwlifnltkgnc
ytdvtnasrtllmdintlqwdekmckifnitnmsvlpeiksncsnfglvksehvpdylni
pitgcigdqqsacigqaifdegeakctygtgvfllintgekvvystcglitticykfndn
dkpkyalegsigtagsgvswllknkliddpseasdimekcenttgvifvpafsglyaprw
rsdarasiygmtfntershivrallegiafqlneivdsltsdmgiemlhvlrcdggmtkn
kpfmqfnsdiintkievskykevtslgaavlaglevkiwdsldsvksllrrsdavfhskm
ddkkrkkktsewnkavertliql