PDB entry 2w2b

View 2w2b on RCSB PDB site
Description: crystal structure of single point mutant tyr20phe p-coumaric acid decarboxylase from lactobacillus plantarum: structural insights into the active site and decarboxylation catalytic mechanism
Class: lyase
Keywords: lyase, active site, coumaric acids, decarboxylation, catalytic mechanism
Deposited on 2008-10-27, released 2009-11-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-11-09, with a file datestamp of 2011-11-04.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.2
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: p-coumaric acid decarboxylase
    Species: Lactobacillus plantarum [TaxId:1590]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W2B
      • engineered mutation (35)
    • Uniprot Q88RY7 (Start-193)
    Domains in SCOPe 2.08: d2w2ba_
  • Chain 'B':
    Compound: p-coumaric acid decarboxylase
    Species: Lactobacillus plantarum [TaxId:1590]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W2B
      • engineered mutation (35)
    • Uniprot Q88RY7 (Start-193)
    Domains in SCOPe 2.08: d2w2bb_
  • Heterogens: ACT, IPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w2bA (A:)
mggshhhhhhgddddkmtktfktlddflgthfiytfdngweyewyakndhtvdyrihggm
vagrwvtdqkadivmltegiykiswteptgtdvaldfmpnekklhgtiffpkwveehpei
tvtyqnehidlmeqsrekyatypklvvpefanitymgdagqnnedviseapykempndir
ngkyfdqnyhrlnk

    Sequence, based on observed residues (ATOM records): (download) 
    >2w2bA (A:)
tktfktlddflgthfiytfdngweyewyakndhtvdyrihggmvagrwvtdqkadivmlt
egiykiswteptgtdvaldfmpnekklhgtiffpkwveehpeitvtyqnehidlmeqsre
kyatypklvvpefanitymgdagqnnedviseapykempndirngkyfdqnyhrlnk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2w2bB (B:)
mggshhhhhhgddddkmtktfktlddflgthfiytfdngweyewyakndhtvdyrihggm
vagrwvtdqkadivmltegiykiswteptgtdvaldfmpnekklhgtiffpkwveehpei
tvtyqnehidlmeqsrekyatypklvvpefanitymgdagqnnedviseapykempndir
ngkyfdqnyhrlnk

    Sequence, based on observed residues (ATOM records): (download) 
    >2w2bB (B:)
tktfktlddflgthfiytfdngweyewyakndhtvdyrihggmvagrwvtdqkadivmlt
egiykiswteptgtdvaldfmpnekklhgtiffpkwveehpeitvtyqnehidlmeqsre
kyatypklvvpefanitymgdagqnnedviseapykempndirngkyfdqnyhrlnk