PDB entry 2w1e

View 2w1e on RCSB PDB site
Description: Structure determination of Aurora Kinase in complex with inhibitor
Class: transferase
Keywords: nucleotide-binding, serine/threonine-protein kinase, transferase, ATP-binding, polymorphism, phosphoprotein, kinase, cancer, aurora, inhibitor, cell cycle
Deposited on 2008-10-17, released 2009-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-10-24, with a file datestamp of 2018-10-19.
Experiment type: XRAY
Resolution: 2.93 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase 6
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W1E (269-End)
    • Uniprot O14965 (Start-268)
    Domains in SCOPe 2.08: d2w1ea1, d2w1ea2
  • Heterogens: L0E, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w1eA (A:)
meskkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrr
eveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitel
analsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppem
iegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardli
srllkhnpsqrpmlrevlehpwitansskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2w1eA (A:)
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvgtldylppemiegrmhdekvdlwslgv
lcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlrev
lehpwitansskh