PDB entry 2w0w
View 2w0w on RCSB PDB site
Description: crystal structure of glmu from haemophilus influenzae in complex with quinazoline inhibitor 2
Class: transferase
Keywords: peptidoglycan synthesis, glmu, bacterial, inhibitor, magnesium, cell shape, transferase, active site, metal-binding, cell wall biogenesis/degradation, multifunctional enzyme, nucleotidyltransferase, acyltransferase, uridyltransferase
Deposited on
2008-10-10, released
2009-11-17
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-06-02.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: 0.25
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: glucosamine-1-phosphate n-acetyltransferase
Species: Haemophilus influenzae [TaxId:727]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2w0wa1, d2w0wa2 - Heterogens: LZS, PG4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2w0wA (A:)
mtkkalsavilaagkgtrmysdlpkvlhtiagkpmvkhvidtahqlgsenihliyghggd
lmrthlaneqvnwvlqteqlgtahavqqaapffkdnenivvlygdaplitketlekliea
kpengialltvnldnptgygriirengnvvaiveqkdanaeqlnikevntgvmvsdgasf
kkwlarvgnnnaqgeyyltdlialanqdncqvvavqatdvmevegannrlqlaaleryfq
nkqasklllegvmiydparfdlrgtlehgkdveidvnviiegnvklgdrvkigtgcvlkn
vvigndveikpysvledsivgekaaigpfsrlrpgaelaaethvgnfveikkstvgkgsk
vnhltyvgdseigsncnigagvitcnydgankfktiigddvfvgsdtqlvapvkvangat
igagttitrdvgenelvitrvaqrhiqgwqrpikkk
Sequence, based on observed residues (ATOM records): (download)
>2w0wA (A:)
kalsavilaagkgtrmysdlpkvlhtiagkpmvkhvidtahqlgsenihliyghggdlmr
thlaneqvnwvlqteqlgtahavqqaapffkdnenivvlygdaplitketleklieakpe
ngialltvnldnptgygriirengnvvaiveqkdanaeqlnikevntgvmvsdgasfkkw
larvgnnnaqgeyyltdlialanqdncqvvavqatdvmevegannrlqlaaleryfqnkq
asklllegvmiydparfdlrgtlehgkdveidvnviiegnvklgdrvkigtgcvlknvvi
gndveikpysvledsivgekaaigpfsrlrpgaelaaethvgnfveikkstvgkgskvnh
ltyvgdseigsncnigagvitcnydgankfktiigddvfvgsdtqlvapvkvangatiga
gttitrdvgenelvitrvaqrhiqgwqrpik