PDB entry 2w0v

View 2w0v on RCSB PDB site
Description: crystal structure of glmu from haemophilus influenzae in complex with quinazoline inhibitor 1
Class: transferase
Keywords: peptidoglycan synthesis, glmu, bacterial, inhibitor, magnesium, cell shape, transferase, active site, metal-binding, cell wall biogenesis/degradation, multifunctional enzyme, nucleotidyltransferase, acyltransferase, uridyltransferase
Deposited on 2008-10-10, released 2009-11-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-06-02.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: 0.2
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucosamine-1-phosphate n-acetyltransferase
    Species: Haemophilus influenzae [TaxId:727]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2w0va1, d2w0va2
  • Heterogens: LZR, PG4, PGE, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w0vA (A:)
mtkkalsavilaagkgtrmysdlpkvlhtiagkpmvkhvidtahqlgsenihliyghggd
lmrthlaneqvnwvlqteqlgtahavqqaapffkdnenivvlygdaplitketlekliea
kpengialltvnldnptgygriirengnvvaiveqkdanaeqlnikevntgvmvsdgasf
kkwlarvgnnnaqgeyyltdlialanqdncqvvavqatdvmevegannrlqlaaleryfq
nkqasklllegvmiydparfdlrgtlehgkdveidvnviiegnvklgdrvkigtgcvlkn
vvigndveikpysvledsivgekaaigpfsrlrpgaelaaethvgnfveikkstvgkgsk
vnhltyvgdseigsncnigagvitcnydgankfktiigddvfvgsdtqlvapvkvangat
igagttitrdvgenelvitrvaqrhiqgwqrpikkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2w0vA (A:)
kalsavilaagkgtrmysdlpkvlhtiagkpmvkhvidtahqlgsenihliyghggdlmr
thlaneqvnwvlqteqlgtahavqqaapffkdnenivvlygdaplitketleklieakpe
ngialltvnldnptgygriirengnvvaiveqkdanaeqlnikevntgvmvsdgasfkkw
larvgnnnaqgeyyltdlialanqdncqvvavqatdvmevegannrlqlaaleryfqnkq
asklllegvmiydparfdlrgtlehgkdveidvnviiegnvklgdrvkigtgcvlknvvi
gndveikpysvledsivgekaaigpfsrlrpgaelaaethvgnfveikkstvgkgskvnh
ltyvgdseigsncnigagvitcnydgankfktiigddvfvgsdtqlvapvkvangatiga
gttitrdvgenelvitrvaqrhiqgwqrpik