SCOPe 2.08: Structural Classification of Proteins

PDB entry 2vz8

View 2vz8 on RCSB PDB site
Description: crystal structure of mammalian fatty acid synthase
Class: transferase
Keywords: transferase, phosphopantetheine, fatty acid synthase, multienzyme, megasynthase, fatty acid synthesis
Deposited on 2008-07-31, released 2008-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.2196
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: fatty acid synthase
Species: Sus scrofa [TaxId:9823]
Database cross-references and differences (RAF-indexed):
- Uniprot A5YV76 (0-End)
  - conflict see remark 9 (833)
Domains in SCOPe 2.08: d2vz8a1, d2vz8a2, d2vz8a3, d2vz8a4, d2vz8a5, d2vz8a6, d2vz8a7, d2vz8a8, d2vz8a9, d2vz8aa, d2vz8ab, d2vz8ac, d2vz8ad
Chain 'B':
Compound: fatty acid synthase
Species: Sus scrofa [TaxId:9823]
Database cross-references and differences (RAF-indexed):
- Uniprot A5YV76 (0-End)
  - conflict see remark 9 (833)

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2vz8A (A:)
meevviagmsgklpesenleefwanliggvdmvtaddrrwkaglyglprrmgklkdlsrf
dasffgvhskqantmdpqlrmllevtyeaivdgginpaslrgtstgvwvgvsssdaseal
srdpetlvgysmigcqrammanrlsfffdfkgpsitidtacsssllalqsayqairggec
saavvgglnvllkpnsslqfmklgmlsqdgtcrsfdaegtgycraeavvavlltkkslar
rvyatilnagtntdgskeqgvtfpsgdvqeqlirslyapagpdpesleyieahgtgtkvg
dpqelngivnalcatrreplligstksnmghpepasgvaalikvllslehgvwapnlhyh
tpnpeipalqdgrlqvvdrplpirggnvginsfgfggsnvhvilqpnsrpapppaqhaal
prllqasgrtleavqtlleqglrhsrdlafvgmlneiaavspvampfrgyavlggeagsq
evqqvpgskrpvwficsgmgaqwqgmglslmrldrfrdsilrsdqalkplglrvsdllls
tdeavlddivssfvsltsiqialidlltslglqpdgiighslgevacgyadgcltqeeav
lssywrgycikeanvlpgamaavglsweeckqrcppgivpachnskdtvtisgpqaamse
flqqlkredvfvkevrtggiafhsyfmesiaptllrqlrkvildpkprskrwlstsipea
qwqgslartfsaeysvnnlvspvlfqealqhvpahavvveiaphallqavlkrslessct
iiplmkkdhrdnlefflsnvgrlhlagvsvnpnglfppvefpaprgtplisphikwdhsq
awdvpsaadfpsgsscssvavykfdvspespdhylvdhcidgrvlfpgtgylwltwktla
ralsqnleetpvvfedvtlhqatilpktgtvslevrlleashafevsdsngsliasgkvy
qwespdpklfdtraavdpadstaefrlsqgdvykdlrlrgydygpffqlvlesdlegnrg
rlqwndswvsfldamlhmsilapgqlglylptrftsiridpvthrqklytlqdttqaadv
vvdrnlntvvaggalflgahssvaprrpqehlkpilekfcftphvesgclagntalqeel
qlcrglaqalqtkvaqqglkmvvpgldgaqapreapqqslprllaaacqlqlngnlqlel
gqvlaqerpllcddpllsglldapalkacvdtalenmaspkmkvvevlagdgqlysripa
llntqpvmdldytatdrnpqaleaaqakleqlhvtqgqwdpanpapgslgkadllvcnca
latlgdpavavgnmaatlkeggflllhtllaghplgemvgfltspeqggrhllsqdqwes
lfagaslhlvalkrsfygsvlflcrqqtpqdspvflsvedtsfrwvdslkdiladassrp
vwlmavgcstsgvvgmvnclrkepgghrircvlvsnlsstspapemhpssselqkvlqgd
lvmnvyrdgawgafrhfpleqdrpekqtehafvnvlsrgdlssirwvcsplhyalpascq
drlcsvyytslnfrdvmlatgklspdsipgkwltrdcmlgmefsgrdasgrrvmgmvpae
glatsvlllqhatwevpstwtleeaasvpivyttayyslvvrgrmqpgesvlihsgsggv
gqaaiaialsrgcrvfttvgsaekraylqarfpqldetcfansrdtsfeqhvlrhtagkg
vdlvlnslaeeklqasvrclaqhgrfleigkfdlsnnhalgmavflknvtfhgilldslf
eeggatwqevsellkagiqegvvqplkctvfprtkveaafrymaqgkhigkvviqvreee
qgpaprglppialtglsktfcpphksyvitgglggfglqlaqwlrlrgaqklvltsrsgi
rtgyqarqvrewrrqgvqvlvstsnassldgarsliteatqlgpvggvfnlamvlrdavl
enqtpeffqdvskpkysgtanldrvtreacpeldyfvifssvscgrgnagqanygfansa
mericekrrhdglpglavqwgaigdvgvvletmgtndtviggtlpqriasclevldlfls
qphpvlssfvlaekkaaaprdgssqkdlvkavahilgirdvasinpdstlvdlgldslmg
vevrqilerehdlvlsmrevrqlslrklqelssktstdadpatptshedspvrqqatlnl
stllvnpegptltrlnsvqsaerplflvhpiegsitvfhglaaklsiptyglqctgaapl
dsiqslasyyiecirqvqpegpyriagysygacvafemcsqlqaqqsatpgnhslflfdg
shtfvlaytqsvrakmtpgceaeaeakamyffvqqftdmeqgkvlealiplqglearvaa
tvdlitqshagldrhalsfaarsfyqklraaenywpqatyhgnvtllraktggaygedlg
adynlsqvcdgkvsvhviegdhrtllegsglesilsiihsclaeprvsvreg

Sequence, based on observed residues (ATOM records): (download)

>2vz8A (A:)
meevviagmsgklpesenleefwanliggvdmvtaddrrwkaglyglprrmgklkdlsrf
dasffgvhskqantmdpqlrmllevtyeaivdgginpaslrgtstgvwvgvsssdaseal
srdpetlvgysmigcqrammanrlsfffdfkgpsitidtacsssllalqsayqairggec
saavvgglnvllkpnsslqfmklgmlsqdgtcrsfdaegtgycraeavvavlltkkslar
rvyatilnagtntdgskeqgvtfpsgdvqeqlirslyapagpdpesleyieahgtgtkvg
dpqelngivnalcatrreplligstksnmghpepasgvaalikvllslehgvwapnlhyh
tpnpeipalqdgrlqvvdrplpirggnvginsfgfggsnvhvilqpnsrpapppaqhaal
prllqasgrtleavqtlleqglrhsrdlafvgmlneiaavspvampfrgyavlggeagsq
evqqvpgskrpvwficsgmgaqwqgmglslmrldrfrdsilrsdqalkplglrvsdllls
tdeavlddivssfvsltsiqialidlltslglqpdgiighslgevacgyadgcltqeeav
lssywrgycikeanvlpgamaavglsweeckqrcppgivpachnskdtvtisgpqaamse
flqqlkredvfvkevrtggiafhsyfmesiaptllrqlrkvildpkprskrwlstsipea
qwqgslartfsaeysvnnlvspvlfqealqhvpahavvveiaphallqavlkrslessct
iiplmkkdhrdnlefflsnvgrlhlagvsvnpnglfppvefpaprgtplisphikwdhsq
awdvpsaadfpsgsscssvavykfdvspespdhylvdhcidgrvlfpgtgylwltwktla
ralsqnleetpvvfedvtlhqatilpktgtvslevrlleashafevsdsngsliasgkvy
qwespdpklfdtraavdpadstaefrlsqgdvykdlrlrgydygpffqlvlesdlegnrg
rlqwndswvsfldamlhmsilapgqlglylptrftsiridpvthrqklytlqdttqaadv
vvdrnlntvvaggalflgahssvaprrpqehlkpilekfcftphvesgclagntallsgl
ldapalkacvdtalenmaspkmkvvevlagdgqlysripallntqpvmdldytatdrnpq
aleaaqakleqlhvtqgqwdpanpapadllvcncaggflllhtldqweslfagaslhlva
lkrsfygsvlflcrqqtpqdspvflsvedtsfrwvdslkdiladassrpvwlmavgcsts
gvvgmvnclrkepgghrircvlvsnlsstspapemhpssselqkvlqgdlvmnvyrdgaw
gafrhfpleqdrpekqtehafvnvlsrgdlssirwvcsplhyalpascqdrlcsvyytsl
nfrdvmlatgklspdsipgkwltrdcmlgmefsgrdasgrrvmgmvpaeglatsvlllqh
atwevpstwtleeaasvpivyttayyslvvrgrmqpgesvlihsgsggvgqaaiaialsr
gcrvfttvgsaekraylqarfpqldetcfansrdtsfeqhvlrhtagkgvdlvlnslaee
klqasvrclaqhgrfleigkfdlsnnhalgmavflknvtfhgilldslfeeggatwqevs
ellkagiqegvvqplkctvfprtkveaafrymaqgkhigkvviqvreeeqgpaprglppi
altglsktfcpphksyvitgglggfglqlaqwlrlrgaqklvltsrsgirtgyqarqvre
wrrqgvqvlvstsnassldgarsliteatqlgpvggvfnlamvvskpkysgtanldrvtr
eacpeldyfvifssvscgrgnagqanygfansamericekrrhdglpglavqwgaigdvg
vvlendtviggtlpqriasclevldlflsqphpvlssfvlae

Chain 'B':
No sequence available.