PDB entry 2vz2

View 2vz2 on RCSB PDB site
Description: human mao b in complex with mofegiline
Class: oxidoreductase
Keywords: oxidoreductase, inhibitor binding, flavoprotein, mitochondrion, transmembrane, human monoamine oxidase, mitochondrion outer membrane, fad, flavin, membrane, mofegiline, acetylation
Deposited on 2008-07-29, released 2008-12-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-07-21, with a file datestamp of 2009-07-17.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.188
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: amine oxidase [flavin-containing] b
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2vz2a1, d2vz2a2
  • Chain 'B':
    Compound: amine oxidase [flavin-containing] b
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2vz2b1, d2vz2b2
  • Heterogens: FAD, MFG, C15, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vz2A (A:)
msnkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsy
vgptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwr
tmddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethev
salwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidq
trenvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivy
ykepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeer
lkklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdr
iyfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpittt
flerhlpsvpgllrliglttifsatalgflahkrgllvrv

    Sequence, based on observed residues (ATOM records): (download) 
    >2vz2A (A:)
nkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsyvg
ptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwrtm
ddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethevsa
lwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidqtr
envlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivyyk
epfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeerlk
klcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdriy
fagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpitttfl
erhlpsvpgllrligltti

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vz2B (B:)
msnkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsy
vgptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwr
tmddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethev
salwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidq
trenvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivy
ykepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeer
lkklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdr
iyfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpittt
flerhlpsvpgllrliglttifsatalgflahkrgllvrv

    Sequence, based on observed residues (ATOM records): (download) 
    >2vz2B (B:)
nkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsyvg
ptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwrtm
ddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethevsa
lwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidqtr
envlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivyyk
epfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeerlk
klcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdriy
fagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpitttfl
erhlpsvpgllrli