PDB entry 2vyt

View 2vyt on RCSB PDB site
Description: The MBT repeats of human SCML2 bind to peptides containing mono methylated lysine.
Class: transcription
Keywords: mono methylated peptides, mbt repeats, transcription, phosphoprotein, alternative splicing, transcription regulation, nucleus, repressor, chromatin, human scml2
Deposited on 2008-07-28, released 2008-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sex comb on midleg-like protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VYT
      • engineered mutation (124)
    • Uniprot Q9UQR0 (Start-220)
    Domains in SCOPe 2.08: d2vyta1, d2vyta2
  • Chain 'B':
    Compound: sex comb on midleg-like protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VYT
    • Uniprot Q9UQR0 (Start-220)
    Domains in SCOPe 2.08: d2vytb1, d2vytb2
  • Heterogens: MLZ, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vytA (A:)
gstssvqrddfhweeylketgsisapsecfrqsqippvndfkvgmkleardprnatsvci
atvigitgarlrlrldgsdnrndfwrlvdspdiqpvgtcekegdllqpplgyqmntsswp
mflletlngsemasatlfkkeppkpplnnfkvgmkleaidkknpylicpatigdvkgdev
hitfdgwsgafdywckydsrdifpagwcrltgdvlqppgts

    Sequence, based on observed residues (ATOM records): (download) 
    >2vytA (A:)
rddfhweeylketgsisapsecfrqsqippvndfkvgmkleardprnatsvciatvigit
garlrlrldgsdnrndfwrlvdspdiqpvgtcekegdllqpplgyqmntsswpmflletl
ngsemasatlfkkeppkpplnnfkvgmkleaidkknpylicpatigdvkgdevhitfdgw
sgafdywckydsrdifpagwcrltgdvlqppgts

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vytB (B:)
gstssvqrddfhweeylketgsisapsecfrqsqippvndfkvgmkleardprnatsvci
atvigitgarlrlrldgsdnrndfwrlvdspdiqpvgtcekegdllqpplgyqmntsswp
mflletlngsemasatlfkkeppkpplnnfkvgmkleaidkknpylicpatigdvkgdev
hitfdgwsgafdywckydsrdifpagwcrltgdvlqppgts

    Sequence, based on observed residues (ATOM records): (download) 
    >2vytB (B:)
ddfhweeylketgsisapsecfrqsqippvndfkvgmkleartsvciatvigitgarlrl
rldgsdnrndfwrlvdspdiqpvgtcekegdsemasatlfkkeppkpplnnfkvgmklea
idkknpylicpatigdvkgdevhitfdgwsgafdywckydsrdifpagwcrltgdvlqpp
gts