PDB entry 2vxl

View 2vxl on RCSB PDB site
Description: screening a limited structure-based library identifies udp-galnac-specific mutants of alpha-1,3 galactosyltransferase
Class: transferase
Keywords: glycosyltransferase, galactosyltransferase, transmembrane, golgi apparatus, enzyme mechanism, glycoprotein, metal-binding, signal-anchor, alpha-1, membrane, manganese, transferase, transferase substrate specificity
Deposited on 2008-07-07, released 2008-09-23
The last revision prior to the SCOPe 2.01 freeze date was dated 2008-12-09, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.192
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: n-acetyllactosaminide alpha-1,3-galactosyltransferase
  Species: Bos taurus [TaxId:9913]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14769 (0-276)
    • engineered mutation (198-201)
  Domains in SCOPe 2.01: d2vxla_
• Heterogens: MN, UDP, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2vxlA (A:)
  klklsdwfnpfkrpevvtmtkwkapvvwegtynravldnyyakqkitvgltvfavgryie
  hyleefltsankhfmvghpvifyimvddvsrmplielgplrsfkvfkikpekrwqdismm
  rmktigehivahiqhevdflfcmdvdqvfqdkfgvetlgesvaqlqawwykadpndftye
  rrkesaayipfgegdfyyagglfggtptqvlnitqecfkgilkdkkndieaqwhdeshln
  kyfllnkptkilspeycwdyhiglpadiklvkmswqt