PDB entry 2vwk

View 2vwk on RCSB PDB site
Description: uracil recognition in archaeal DNA polymerases captured by x-ray crystallography. v93q polymerase variant
Class: DNA replication
Keywords: DNA replication, multifunctional enzyme, nucleotidyltransferase, DNA-directed DNA polymerase, transferase, exonuclease, DNA-binding, DNA polymerase, uracil, archaea, nuclease, hydrolase, DNA repair
Deposited on 2008-06-26, released 2008-07-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.22
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase
    Species: Thermococcus gorgonarius [TaxId:71997]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56689 (0-772)
      • engineered mutation (92)
      • conflict (150)
      • conflict (173)
      • engineered mutation (214)
    Domains in SCOPe 2.08: d2vwka1, d2vwka2
  • Heterogens: NA, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2vwkA (A:)
mildtdyitedgkpvirifkkengefkidydrnfepyiyallkddsaiedvkkitaerhg
ttvrvvraekvkkkflgrpievwklyfthpqdqpairdkikehpavvdiyeydipfakry
lidkglipmegdeelkmlafdietlyhegekfaegpilmisyadeegarvitwrnidlpy
vdvvstekemikrflkvvkekdpdvlityngdnfafaylkkrseklgvkfilgregsepk
iqrmgdrfavevkgrihfdlypvirrtinlptytleavyeaifgqpkekvyaeeiaqawe
tgeglervarysmedakvtyelgkeffpmeaqlsrlvgqslwdvsrsstgnlvewfllrk
ayernelapnkpderelarrresyaggyvkeperglwenivyldfrslypsiiithnvsp
dtlnregceeydvapqvghkfckdfpgfipsllgdlleerqkvkkkmkatidpiekklld
yrqraikilansfygyygyakarwyckecaesvtawgrqyiettireieekfgfkvlyad
tdgffatipgadaetvkkkakefldyinaklpglleleyegfykrgffvtkkkyavidee
dkittrgleivrrdwseiaketqarvleailkhgdveeavrivkevteklskyevppekl
viyeqitrdlkdykatgphvavakrlaargikirpgtvisyivlkgsgrigdraipfdef
dpakhkydaeyyienqvlpaverilrafgyrkedlryqktrqvglgawlkpkt