PDB entry 2vvq

View 2vvq on RCSB PDB site
Description: crystal structure of mycobacterium tuberculosis ribose-5-phosphate isomerase b in complex with the inhibitor 5-deoxy-5-phospho-d-ribonate
Class: isomerase
Keywords: pentose phosphate pathway, rpib, rv2465c, isomerase, carbohydrate metabolism
Deposited on 2008-06-10, released 2008-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.161
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribose-5-phosphate isomerase b
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vvqa_
  • Chain 'B':
    Compound: ribose-5-phosphate isomerase b
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vvqb_
  • Chain 'C':
    Compound: ribose-5-phosphate isomerase b
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vvqc_
  • Chain 'D':
    Compound: ribose-5-phosphate isomerase b
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vvqd_
  • Chain 'E':
    Compound: ribose-5-phosphate isomerase b
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vvqe_
  • Heterogens: R10, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vvqA (A:)
msgmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvad
pgslgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaea
laivdafvttpwskaqrhqrridilaeyertheappvpgapa

    Sequence, based on observed residues (ATOM records): (download) 
    >2vvqA (A:)
gmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvadpg
slgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaeala
ivdafvttpwskaqrhqrridilaeyertheappvpg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vvqB (B:)
msgmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvad
pgslgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaea
laivdafvttpwskaqrhqrridilaeyertheappvpgapa

    Sequence, based on observed residues (ATOM records): (download) 
    >2vvqB (B:)
gmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvadpg
slgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaeala
ivdafvttpwskaqrhqrridilaeyertheappvpg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vvqC (C:)
msgmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvad
pgslgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaea
laivdafvttpwskaqrhqrridilaeyertheappvpgapa

    Sequence, based on observed residues (ATOM records): (download) 
    >2vvqC (C:)
gmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvadpg
slgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaeala
ivdafvttpwskaqrhqrridilaeyertheappvpgap

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vvqD (D:)
msgmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvad
pgslgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaea
laivdafvttpwskaqrhqrridilaeyertheappvpgapa

    Sequence, based on observed residues (ATOM records): (download) 
    >2vvqD (D:)
sgmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvadp
gslgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaeal
aivdafvttpwskaqrhqrridilaeyertheappvpg

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2vvqE (E:)
msgmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvad
pgslgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaea
laivdafvttpwskaqrhqrridilaeyertheappvpgapa

    Sequence, based on observed residues (ATOM records): (download) 
    >2vvqE (E:)
gmrvylgadhagyelkqriiehlkqtghepidcgalrydadddypafciaaatrtvadpg
slgivlggsgngeqiaankvpgarcalawsvqtaalarehnnaqligiggrmhtvaeala
ivdafvttpwskaqrhqrridilaeyertheappvpg