PDB entry 2vv1

View 2vv1 on RCSB PDB site
Description: hPPARgamma Ligand binding domain in complex with 4-HDHA
Class: receptor
Keywords: transcription regulation, alternative splicing, ligand binding domain, nuclear receptor, diabetes mellitus, zinc-finger, DNA-binding, polymorphism, transcription, zinc, obesity, nucleus, receptor, activator, oxidised fatty acid, transcription factor, metal-binding, phosphoprotein, disease mutation
Deposited on 2008-06-02, released 2008-08-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vv1a_
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VV1
      • conflict (7)
    • Uniprot P37231
    Domains in SCOPe 2.08: d2vv1b_
  • Heterogens: 4HD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vv1A (A:)
galnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
ikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkyg
vheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldd
sdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtd
lrqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records): (download) 
    >2vv1A (A:)
pesadlralakhlydsyiksfpltkakarailtgttdkspfviydmnslmmgedkievai
rifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgv
lisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpg
llnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikkt
etdmslhpllqeiykd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vv1B (B:)
galnpessdlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
ikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkyg
vheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldd
sdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtd
lrqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records): (download) 
    >2vv1B (B:)
sdlralakhlydsyiksfpltkakarailtgkdkspfviydmnslmmgevairifqgcqf
rsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgf
mtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpie
diqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktpllqeiy